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Found 724 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes (CLVer): Extension Study

A
Anna Neyman
7 years - 18 years
All genders
The aim of this study is to learn more about the long-term effectiveness of hybrid closed-loop system and verapamil in treating type 1 diabetes.
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A Phase I Study of Intra-Tumoral Injections of Ex Vivo Expanded Natural Killer Cells in Children and Young Adults With Recurrent or Progressive Supratentorial Malignant Brain Tumors

S
Scott Coven
1 years - 38 years
All genders
Phase 1
What is this study about?This phase I trial tests the safety, side effects, and best dose of ex vivo expanded natural killer cells in treating patients with cancerous (malignant) tumors affecting the upper part of the brain (supratentorial) that have come back (recurrent) or that are growing, spreading, or getting …
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A Pivotal, Prospective, Open-label, Multi-center Study of Safety and Effectiveness of Cochlear Implantation in an Expanded Population of Adults With Bilateral Sensorineural Hearing Loss

R
Rick Nelson, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This study aims to evaluate the safety and efficacy of cochlear implantation for adults with bilateral sensorineural hearing loss who currently do not meet the FDA-approved indications for cochlear implantation. Following cochlear implantation, participants will complete speech perception assessments and questionnaires over the course …
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NF119: A Phase 2, Open-Label, Single Arm, Non-Controlled, Single-Stage Study to Evaluate the Safety and Effects of HLX-1502 in Patients with Plexiform Neurofibroma and Neurofibromatosis Type 1

S
Steven Rhodes
16 years or above
All genders
Phase 2
What is the purpose of this study?The trial will be an open label, single arm, phase 2 study in 20 participants. The study will assess the tolerability and efficacy of HLX-1502 in participants with NF1 16 years of age or older with progressive and/or symptomatic PN. THIS STUDY IS ENROLLING …
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Study on Investigational Medication for Candidemia and Invasive Candidiasis

N
Nicolas Barros, MD
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the effects and safety of an investigational medication for treating candidemia and invasive candidiasis, which are serious fungal infections caused by Candida species. Candidemia is a bloodstream infection, while invasive candidiasis occurs when the infection spreads beyond the bloodstream to other parts of the body.Participants will receive …
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Clinical Trial Designed to Assess the Safety and Effectiveness of the KOKO Device In Treating Primary Abnormal Postpartum Uterine Bleeding ("APUB") or Hemorrhage ("PPH")

C
Christina M. Scifres, MD
18 years - 100 years
Female
Interventional
What is the purpose of this study?The sponsor of this research study, KOKO Medical Inc, is evaluating a medical device to control and treat abnormal postpartum uterine bleeding or hemorrhage (excessive bleeding). The device is called the KOKO device and its use in this study is experimental. The purpose of …
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Indiana University GI Neuromuscular Pathology Prospective Registry

J
John Wo, MD
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this study is to determine if ICC abnormalities of the stomach and proximal jejunum can be used as a biologic marker in predicting clinical outcome in patients undergoing surgical implantation of GES for severe gastroparesis. The primary aim is to determine …
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Concentration, H2O intake, Urine, Dehydration

A
Andrew Schwaderer, MD
12 years - 18 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The purpose of this study is to determine if urine color can be used to determine urine concentration and hydration status. We will test methodology that can be easily performed by families to monitor hydration status which is an important health consideration. Our primary …
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Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease

R
Raghu Motaganahalli, MD
18 years - 79 years
All genders
Observational
The study objective is to evaluate real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System in patients at standard risk fordverse events from carotid endarterectomy
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Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures

K
Karl Shively
B
Brian Mullis, MD
18 years - 80 years
All genders
Phase 3
Interventional
The proposed study is a two arm, pragmatic, randomized controlled multicenter Phase IIIy trial. 1,000 patients with tibia fractures treated with intramedullary (IM)will be randomized into two treatment arms. The control arm will receive standard paingement and no NSAIDs. The treatment arm will receive standard pain management plus up toweeks …
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