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Found 712 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Long-Term Effects of Investigational Treatment in Phenylketonuria (PKU)

M
Melissa Lah, MD
100 years or below
All genders
Observational
This study investigates the effects of long-term treatment on people with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine, which can lead to harmful levels in the body. The purpose of this study is to evaluate immune and inflammatory responses in participants receiving …
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Feasibility of the Venous Excess in Ultrasound Score and its correlation with elevated CVP and RAP in Pediatric CVICU patients

M
Michael David Lintner-Rivera
17 years or below
All genders
Observational
What is the purpose of this study?There is extremely limited knowledge of the applicability of VEXUS in critically ill children. VExUS was recently evaluated in a cohort of pediatric ICU patients and was found to correlate well with CVP measurements. (11) To date, there have been no studies determining the …
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Investigating the Addition of Venetoclax to Chemotherapy in Children with Relapsed Acute Myeloid Leukemia (AML)

S
Sandeep Batra, MD
29 days - 21 years
All genders
Phase 3
This study investigates the treatment of acute myeloid leukemia (AML) in children, adolescents, and young adults who have experienced a relapse. The purpose is to see if adding an investigational medication to a standard chemotherapy treatment can improve outcomes. Acute myeloid leukemia is a type of cancer that affects the …
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A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease

C
Cary Mariash, MD
18 years - 75 years
All genders
Phase 2/3
Interventional
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …
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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

J
Joel Corvera, MD
18 years - 100 years
All genders
Observational
An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subjects treated with GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System as a part of routine clinical practice. This post-market registry for the GORE® TAG® Conformable Thoracic Stent …
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Study on Hemolytic Disease of the Fetus and Newborn

H
Hiba Mustafa, MD
100 years or below
All genders
This study investigates the condition known as Hemolytic Disease of the Fetus and Newborn (HDFN). HDFN occurs when a pregnant person's immune system attacks the red blood cells of their fetus, leading to anemia and other complications. This study is a global, prospective registry that collects data from pregnant individuals …
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Investigating Treatment for Children with Favorable Histology Wilms Tumors

M
Marissa Just
30 years or below
All genders
Phase 3
This study investigates treatment strategies for children with favorable histology Wilms tumors (FHWT), which is a common type of kidney cancer in children. The study aims to use risk factors, such as tumor histology, biology, and response to therapy, to determine the most effective treatment plan. Wilms Tumor is a …
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Study on Investigational Medication for PSC (Primary Sclerosing Cholangitis)

R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Phase 2
Interventional
This study investigates the safety and effectiveness of an investigational medication for primary sclerosing cholangitis (PSC). PSC is a liver disease that causes inflammation and scarring of the bile ducts, which can lead to liver damage. This study involves two parts. In Part 1, the safety and tolerability of two …
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Investigating Long-Term Safety of an Investigational Treatment for Pompe Disease, a Rare Glycogen Storage Disorder

M
Melissa Lah, MD
18 years - 100 years
All genders
Observational
This study investigates the long-term safety of an investigational treatment for Pompe disease, a rare disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The purpose is to gather information on potential risks associated with the treatment, including infusion-related reactions and medication errors.Participants will …
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Studying the Safety of a Skin Patch for Peanut Allergy in Young Children

G
Girish Vitalpur, MD
1 years - 3 years
All genders
Phase 3
Interventional
This study investigates the safety of an investigational treatment for peanut allergy in children aged 1 through 3 years. Peanut allergy is a condition where the body's immune system reacts to peanuts, causing allergic reactions. The purpose of this study is to assess the safety of a skin patch treatment, …
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