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Found 702 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study of Investigational Medication with Chemotherapy for Certain Blood Cancers

B
Brian Weiss
1 year - 18 years
All genders
Phase 1
This study investigates the safety and best dose of an investigational medication combined with chemotherapy drugs, fludarabine and cytarabine, for treating certain blood cancers. The cancers include acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and juvenile myelomonocytic leukemia (JMML) that have not responded to previous treatment or have returned after …
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A Phase II Trial Evaluating Chemotherapy Followed by Response-Based Reduced Radiation Therapy for Patients With Central Nervous System Germinomas

S
Sandeep Batra, MD
3 years - 30 years
All genders
Phase 2
What is the purpose of this study?This phase II trial studies how well lower dose radiotherapy after chemotherapy works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class …
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Study on Cognitive Effects of Childhood-Onset Systemic Lupus Erythematosus

S
Stacey Tarvin, MD
21 years or below
All genders
Observational
This study investigates how childhood-onset neuropsychiatric systemic lupus erythematosus (NPSLE) affects cognitive functions over time. Systemic lupus erythematosus (SLE) is a disease where the immune system attacks the body, causing inflammation and damage. The study uses a tool called pedANAM to assess cognitive and behavioral functions in children with this …
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Study of Investigational Medication for Teens with Belly Pain and Bathroom Trouble

E
Erik David Andrewski
12 years - 17 years
All genders
Interventional
This study investigates the effects of an investigational medication for treating Irritable Bowel Syndrome with Constipation (IBS-C) in teenagers. IBS-C is a condition where the belly hurts and there is trouble going to the bathroom. This study is for children aged 12 to less than 18 years old.During the study, …
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PREVENTion of Clot in Orthopaedic Trauma (PREVENT CLOT): A Randomized Pragmatic Trial Comparing the Complications and Safety of Blood Clot Prevention Medicines Used in Orthopaedic Trauma Patients

R
Roman Natoli, MD
100 years or below
All genders
The purpose of this research study is to help determine the best treatment for preventing blood clots that are formed following trauma that could potentially lead to death. At the moment researchers do not know if using medications called low molecular weight heparin or aspirin is better in preventing life …
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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study (STOP360AG)

C
Cynthia Brown, MD
6 years or above
All genders
Phase 4
Interventional
The purpose of this study is to look at pulmonary exacerbations in people with cysticbrosis (CF) that need to be treated with antibiotics given through a tube inserted into a vein (intravenous or IV). A pulmonary exacerbation is a worsening of respiratory symptoms inwith CF that needs medical intervention. Both …
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A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Determine the Safety and Efficacy of Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

D
Damien G. Patel, MD
40 years - 100 years
All genders
Phase 2
Interventional
What is the goal of this study?Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The purpose of this study is to determine the safety and efficacy of oral ifetroban compared to placebo in subjects with IPF. THIS STUDY IS ENROLLING BY INVITATION ONLY  
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Investigating Barriers to Exercise in Women with Metastatic Breast Cancer

T
Tarah Ballinger, MD
18 years - 100 years
Female
This study investigates why women with metastatic breast cancer choose not to participate in exercise programs designed for their needs. Metastatic breast cancer is when cancer has spread beyond the breast to other parts of the body. Understanding the reasons for non-participation can help improve future program designs.Participants will complete …
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Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Phase 3
Interventional
This study investigates the safety and tolerability of an investigational medication in young people with schizophrenia or bipolar disorder.  Schizophrenia is a mental disorder that affects how a person thinks, feels, and behaves. Bipolar disorder is a condition that causes extreme mood swings, including emotional highs (mania or hypomania) and lows (depression)
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A Multicenter, Open-Label, Extension Clinical trial to evaluate Safety and Efficacy of Saroglitazar Magnesium in Participants with Primary Biliary Cholangitis (PBC)

R
Raj Vuppalanchi, MD
18 years - 100 years
All genders
Interventional
What is the purpose of this study?This clinical trial (a medical research study) is an open-label extension of a previous research study, SARO.21.001, which evaluates the efficacy (improvement in liver enzymes and lipid profiles) and safety (side effects) of Saroglitazar Magnesium in participants with a medical condition known as Primary …
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