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Found 683 results for in-health

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Pulmonary Hypertension Association Registry (PHAR)

R
Roberto Bernardo
All genders
Observational
What is this study about?The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collectswith PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people …

Cast or Operation for Medial Epicondyle Fracture Treatment in Children (COMET)

E
Erika Daley
7 years - 17 years
All genders
Interventional
This protocol describes a multicenter, prospective randomized superiority trial of medialdyle fracture treatments comparing functional outcomes between children treated withve reduction and fixation or non-operative immobilization.

Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta

J
Joel Corvera, MD
18 years - 100 years
All genders
Interventional
What is this study about?The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch. THIS STUDY IS ENROLLING BY INVITATION ONLY

A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)

A
Ankit Desai
18 years - 85 years
All genders
Phase 3
Interventional
What is the purpose of this study?The study will evaluate the efficacy and safety of chronic oral levosimendan compared with placebo in PH-HFpEF subjects. This subject population represents a large and growing group with no established therapies to treat their PVD and RV dysfunction. Levosimendan and its prolonged active metabolite, …

A Multicenter, Open-label, Randomized, Bupivacaine-Controlled Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Aged 0 to Less Than 6 Years Undergoing Cardiac Surgery

B
Brandon Tanner
All genders
Phase 1
Interventional
This Phase 1, multicenter, open-label, randomized, bupivacaine-controlled study is designed to evaluate the pharmacokinetics (PK) and safety of EXPAREL vs. bupivacaine HCl for postsurgical analgesia in pediatric subjects aged 0 to less than 6 years of age undergoing cardiac surgery, utilizing local infiltration analgesia (LIA). THIS STUDY IS ENROLLING BY INVITATION …

A Prospective, Single-Arm Multi-Center Study of the HARMONIC 700, 5 mm Diameter Shears with Advanced Hemostasis in Pediatric Surgical Procedures (General) and Adult Surgical Procedures (General, Gynecological, Urological, and Thoracic)

T
Troy Markel, MD
All genders
Interventional
What is the purpose of this study?The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical procedures.THIS STUDY IS ENROLLING BY INVITATION ONLY - …

Patterns of cerebral oxygenation after ventricular reservoir placement and CSF removal: a pilot study

B
Beatrice Stefanescu
All genders
Observational
What is the purpose of this study?About 25% of babies born prematurely (before 32 weeks gestation) develop brain bleeds (intraventricular hemorrhage or IVH), which could progress to the serious complication of post-hemorrhagic hydrocephalus (PHH). Infants with PHH may require neurosurgical intervention to relieve the increased pressure that builds up within …

PREVENT ALL ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …

Empagliflozin and Physical Function in CKD (EMPA-FUNCTION) Feasibility Study

K
Kenneth Lim
18 years - 100 years
All genders
Interventional
What is the purpose of this study?The purpose of the study is to assess the therapeutic benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors in improving physical function in End Stage Renal disease (ESRD) patients.  The study is using the drug Empagliflozin, a FDA approved drug for patients with advanced CKD. …

Attenuating DEPression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors (ADEPT-ICU)

B
Babar Khan, MD
50 years - 100 years
All genders
Interventional
What is the purpose of this study?Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer’s disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with Internet CBT …
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