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Found 706 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Investigational Medication for Depressive Episodes in Youth with Bipolar Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Interventional
This study investigates the use of an investigational medication for treating depressive episodes in young people aged 10 to 17 years with Bipolar I Disorder. The study aims to see if the investigational medication is safe and works well in young people.Bipolar I Disorder is a mental health condition that …
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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

M
Michael Hobson, MD
3 days - 2 years
All genders
Interventional
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
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A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis

C
Craig Lammert, MD
18 years - 75 years
All genders
Observational
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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PREVENT ALL ALS

C
Cynthia Bodkin, MD
18 years - 100 years
All genders
Observational
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
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A Phase 3, Randomized, Double-Blind, Safety, and Efficacy Study ofRuxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

D
David Rosmarin
2 years - 11 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this study is to to evaluate the safety and efficacy of ruxolitinib cream in pediatric participants with nonsegmental vitiligo. THIS STUDY IS ENROLLING BY INVITATION ONLY
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Neonatal Caloric Absorption in Relation to Growth Outcomes and Nutrition

K
Katie Huff
34 weeks - 100 years
All genders
Observational
The goal of this study is to learn more about how babies in the NICU are able to take in and use the food they are getting. We want to follow babies during their stay in the NICU and measure their input and output, essentially, what’s in their diet and …
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A Randomized Trial of the Insulin-only Bionic Pancreas in Cystic Fibrosis Related Diabetes

V
Viral Shah
14 years - 100 years
All genders
Observational
What is the purpose of this study?To compare the efficacy and safety of the BP relative to usual care (which includes CGM) in a 13-week randomized trial in individuals ≥ 14 years old with CFRD.To assess the sustainability of BP use, efficacy, and safety over an additional 13 weeks after …
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The Return of the Pancreas: Evaluating impact of CFTR modulators on pancreatic function

M
Molly Bozic, MD
18 years or below
All genders
Interventional
What is the purpose of this study?This study aims to see how often children with cystic fibrosis (CF) develop normal pancreatic function after starting treatment with CFTR modulators and to identify what factors might influence this change. We will also look at whether it is safe for these patients to …
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Validating Ten Test efficacy of sensation in patients with traumatic upper extremity injuries

E
Erin Weber
5 years - 100 years
All genders
Interventional
What will happen during the study?This study aims to enhance our understanding of the effectiveness of a noninvasive, simplistic examination for hand sensation to help determine the need for invasive intervention. Hopefully, this will lead to improved quality of care provided for individuals with traumatic nerve injuries to the upper …
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