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Found 702 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Development of trial-ready cohort to facilitate rapid enrollment into Alzheimer’s trials for participants with Down Syndrome (Trial Ready Cohort—Down Syndrome (TRC-DS)

J
Jill Fostad
35 years - 55 years
All genders
Interventional
Who is Eligible Ages 35-55 Must be willing to complete PET scan What is Involved Onsite visits at the IUH Neuroscience Center Visits at the IUH Neuroscience Center every 16 months Compensation Compensation available via payment card for each completed appointment
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Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease

R
Raghu Motaganahalli, MD
18 years - 79 years
All genders
Observational
The study objective is to evaluate real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System in patients at standard risk fordverse events from carotid endarterectomy
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Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy (DMD)

J
John Parent, MD
7 years or above
Male
Phase 2
Interventional
What is the purpose of this study?Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss ofbulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, an dvitably premature death of affected young men in their late twenties. DMD is the mostgenetic disorder …
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A Randomized Controlled Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy for the Management of Severe Open Tibia Fracture Wounds

Y
Yohan Jang
18 years - 100 years
All genders
Interventional
What is this study about?Open tibia fracture complications are debilitating for patients. NPWT is the current standard of care for temporary wound management of severe open fractures requiring multiple debridements. Emerging comparative studies suggest that the antibiotic bead pouch may significantly reduce the risk of open fracture infection and its …
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Investigating Dialysis Access Methods in Female Patients with Kidney Failure

D
David A. Peterson, MD
18 years or above
Female
Phase 3
Interventional
This study investigates the differences between two dialysis access methods in female patients with end-stage renal disease (ESRD) who need hemodialysis. The purpose is to compare catheter-free days and infection severity between patients using two different types of access methods over 12 months.Participants will be randomly assigned to one of …
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Sympathetic Nerve Activity and Cardiovascular Events

T
Thomas Everett
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during supportive care for cardiac arrest, and to risk stratify patients for recurrence of atrial …
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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

M
Michael Hobson, MD
3 days - 2 years
All genders
Interventional
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
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A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis

C
Craig Lammert, MD
18 years - 75 years
All genders
Observational
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
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Role of neutrophil-specific NOX2 in alcohol-induced liver injury

S
Suthat Liangpunsakul, MD
18 years - 70 years
Accepts healthy volunteer
All genders
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
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Study on Investigational Medication for Relapsing Multiple Sclerosis

A
Ajay Gupta
18 years - 55 years
All genders
Interventional
The purpose of this study is to investigate an investigational medication for people with relapsing multiple sclerosis (RMS). RMS is a condition where the immune system mistakenly attacks the protective covering of nerves, causing symptoms like fatigue, vision problems, and difficulty with coordination. This study will compare the investigational medication …
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