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Found 725 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Oral Ifetroban in Subjects With Duchenne Muscular Dystrophy (DMD)

J
John Parent, MD
7 years or above
Male
Phase 2
Interventional
What is the purpose of this study?Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss ofbulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, an dvitably premature death of affected young men in their late twenties. DMD is the mostgenetic disorder …
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Longitudinal Study of Genetic Causes of Intrahepatic Cholestasis (LOGIC) (LOGIC)

J
Jean Molleston, MD
25 years or below
All genders
Observational
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
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Promoting Shared Decision Making in Periviable Care

B
Brownsyne Tucker Edmonds, MD
18 years - 100 years
All genders
The purpose of this study is to test the Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) among  pregnant women (and their significant others) who are hospitalized for a potential periviable (early premature) delivery.  We will evaluate the Periviable GOALS decision Support Tool's effects on shared …
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Optical Diagnosis Versus Laser Measurement of Polyps' Size During Colonoscopy and Implications for Surveillance

D
Douglas Rex, MD
18 years or above
Accepts healthy volunteer
All genders
What is the purpose of this study?Recent updates of the guidelines on polyp surveillance of the American Society of Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE)gly focus on size of polyps as an important indicator of malignant transformation to(CRC). However, the interobserver variability in polyp size assessment …
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Investigating Dialysis Access Methods in Female Patients with Kidney Failure

D
David A. Peterson, MD
18 years or above
Female
Phase 3
Interventional
This study investigates the differences between two dialysis access methods in female patients with end-stage renal disease (ESRD) who need hemodialysis. The purpose is to compare catheter-free days and infection severity between patients using two different types of access methods over 12 months.Participants will be randomly assigned to one of …
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Blood Collection for Research Studies Related to Asthma, Cystic Fibrosis and Other Pulmonary Disorders

K
Kirsten Kloepfer, MD
5 years - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?The purpose of this study is to collect blood samples from people ages 5 years and older who are healthy volunteers or patients with CF or other pulmonary disorders. The blood samples will be used for a variety of studies related to CF, asthma, …
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Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures (FROST)

R
Roman Natoli, MD
18 years or above
All genders
Observational
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will bed prospectively in this registry. All patients are treated and followed at 6 weeks, 6hs and 1 year postoperative always following the local standard of care (routine) visithedule up to 36 months if required. Data collection includes patient …
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Sympathetic Nerve Activity and Cardiovascular Events

T
Thomas Everett
18 years - 100 years
All genders
What is the purpose of this study?The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during supportive care for cardiac arrest, and to risk stratify patients for recurrence of atrial …
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Study on Investigational Medication for Depressive Episodes in Youth with Bipolar Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Interventional
This study investigates the use of an investigational medication for treating depressive episodes in young people aged 10 to 17 years with Bipolar I Disorder. The study aims to see if the investigational medication is safe and works well in young people.Bipolar I Disorder is a mental health condition that …
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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

M
Michael Hobson, MD
3 days - 2 years
All genders
Interventional
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
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