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Found 725 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Music and Imagery for Managing Sickle Cell Disease Symptoms

S
Sheri Robb
14 years - 22 years
All genders
Interventional
This study investigates the use of music and imagery to support self-care management in adolescents and young adults with sickle cell disease. Sickle cell disease (SCD) is a condition where red blood cells are shaped like a sickle, which can block blood flow and cause pain. The purpose of this …
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Phase III Trial of Stereotactic Radiosurgery (SRS) versus Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for Brain Metastases from Small Cell Lung Cancer.

K
Kevin Shiue
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. …
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Study of Genetic Factors in Heart and Blood Vessel Diseases

L
Larry Markham
100 years or below
All genders
This study investigates the genetic causes of thoracic aortic aneurysm (TAA) and other aortic diseases. The purpose is to find new genes that may cause these conditions and understand how genetics can affect the severity of aortic and valve diseases.Participants will provide blood and urine samples. If blood samples cannot …
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TArgeting Type 1 Diabetes Using POLyamines (TADPOL) (TADPOL)

E
Emily Sims, MD
6 years - 40 years
All genders
Phase 2
Interventional
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question[s] it aims to answer are:Does it reduce stress on the cells that make insulin?Does it preserve what is left of the body's insulin production? Participants will …
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A Protocol for Children and Young Adults Diagnosed with a Central Nervous System (CNS) Tumor to Assess Cognitive, Quality of Life (QOL), and Comprehensive Effects of Therapies

S
Scott Coven
39 years or below
All genders
What is the purpose of this study?To longitudinally assess cognitive outcomes using an a neurocognitive screening battery in children and young adults diagnosed with a CNS tumor. To longitudinally assess the impact of specific therapies on the QOL in children and young adults diagnosed with a CNS tumor.To longitudinally assess …
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Investigational Treatment for a Type of White Blood Cell Disease

A
Anthony Ross
180 days - 22 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
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A multicenter, single-arm, pivotal study to evaluate the safety and efficacy of the CGuard Prime carotid stent system (80cm) used in conjunction with the FDA-cleared ENROUTE Transcarotid Neuroprotection System (NPS) in patients undergoing carotid artery stenting via the Transcarotid Artery Revascularization (TCAR) approach.

R
Raghu Motaganahalli, MD
18 years - 79 years
All genders
Interventional
What is the purpose of this study?The objective of this study is to evaluate acute device and technical success of the CGuard Prime™ Carotid Stent System (80cm) when used in conjunction with the Enroute NPS during Transcarotid Artery Revascularization procedures in the treatment of carotid artery stenosis in spatients at …
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Investigation of Blood Samples from Stage IV Non-Small Cell Lung Cancer Patients

V
Vijay Khatri
100 years or below
All genders
This study investigates the collection of fresh blood from patients with Stage IV Non-Small Cell Lung Cancer (NSCLC). NSCLC is a type of lung cancer that is characterized by the uncontrolled growth of cells in the lung tissue. Stage IV indicates that the cancer has spread beyond the lungs to …
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Congenital Heart Surgeons' Society (CHSS) Studies in Congenital Heart Disease

M
Mark Turrentine, MD
All genders
What is the purpose of this study?The purpose of this study is to participate in a registry of patients with congenital heart disease. Patient data from the United States, Canada, and South America (whose institutions of care are members of the Congenital Heart Surgeon’s Society) will be submitted to this …
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Case Studies of Rare Gene Variants Linked to Parkinson’s Disease

T
Tatiana Foroud
18 years - 100 years
All genders
What is the purpose of this study?Parkinson disease (PD) is s the second most common movement disorder, occurring in 1-3% of the population. It is a complex condition with varied symptomatology, age of onset, and rate of progression. Much has been learned about PD in the last several decades including …
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