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Found 701 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigational Treatment for a Type of White Blood Cell Disease

A
Anthony Ross
180 days - 22 years
All genders
Phase 2
Interventional
This study investigates an investigational medication for treating Langerhans cell histiocytosis (LCH), a disease where the body makes too many immature Langerhans cells, a type of white blood cell. These cells can build up and form tumors in organs like bones, skin, and lungs, causing damage. The purpose of the …
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A multicenter, single-arm, pivotal study to evaluate the safety and efficacy of the CGuard Prime carotid stent system (80cm) used in conjunction with the FDA-cleared ENROUTE Transcarotid Neuroprotection System (NPS) in patients undergoing carotid artery stenting via the Transcarotid Artery Revascularization (TCAR) approach.

R
Raghu Motaganahalli, MD
18 years - 79 years
All genders
Interventional
What is the purpose of this study?The objective of this study is to evaluate acute device and technical success of the CGuard Prime™ Carotid Stent System (80cm) when used in conjunction with the Enroute NPS during Transcarotid Artery Revascularization procedures in the treatment of carotid artery stenosis in spatients at …
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Study for Measuring Plasma Free Hemoglobin in ECMO and VAD Patients

M
Michelle Zimmerman, MD
100 years or below
All genders
Observational
This study investigates the validation of an investigational medical device for measuring plasma free hemoglobin in patients using ECMO or VAD life-support machines. Plasma free hemoglobin is a substance that indicates hemolysis, which is the breakdown of red blood cells. The purpose of this study is to ensure the device …
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Study on Investigational Medicine for Liver Disease

R
Raj Vuppalanchi, MD
18 years - 80 years
All genders
Phase 3
Interventional
This study investigates the safety and effectiveness of an investigational medication in people with compensated cirrhosis caused by NASH/MASH. Cirrhosis is a condition where the liver becomes scarred and cannot work properly. NASH/MASH stands for non-alcoholic steatohepatitis and metabolic dysfunction-associated steatohepatitis, which are liver diseases that cause inflammation and scarring.Participants …
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Investigation of Blood Samples from Stage IV Non-Small Cell Lung Cancer Patients

V
Vijay Khatri
100 years or below
All genders
This study investigates the collection of fresh blood from patients with Stage IV Non-Small Cell Lung Cancer (NSCLC). NSCLC is a type of lung cancer that is characterized by the uncontrolled growth of cells in the lung tissue. Stage IV indicates that the cancer has spread beyond the lungs to …
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Congenital Heart Surgeons' Society (CHSS) Studies in Congenital Heart Disease

M
Mark Turrentine, MD
All genders
What is the purpose of this study?The purpose of this study is to participate in a registry of patients with congenital heart disease. Patient data from the United States, Canada, and South America (whose institutions of care are members of the Congenital Heart Surgeon’s Society) will be submitted to this …
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Case Studies of Rare Gene Variants Linked to Parkinson’s Disease

T
Tatiana Foroud
18 years - 100 years
All genders
What is the purpose of this study?Parkinson disease (PD) is s the second most common movement disorder, occurring in 1-3% of the population. It is a complex condition with varied symptomatology, age of onset, and rate of progression. Much has been learned about PD in the last several decades including …
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Clinical and Genetic Evaluation of Patients With Undiagnosed Disorders Through the Undiagnosed Diseases Network

S
Stephanie Ware, MD
1 months - 100 years
Accepts healthy volunteer
All genders
What is the purpose of this study?This research study called the Undiagnosed Diseases Network (UDN). UDN is a group of medical and research centers across the United States. The clinical sites will perform extensive phenotyping, genetic analyses, and functional studies of potential disease-causing variants. The testing performed on patients involves …
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Quality Technical Agreement for Thymus Fragments collection

J
Jeremy Herrmann, MD
15 years or below
All genders
What is the purpose of this study?SANOFI Genzyme collects thymus fragments from pediatric cardiothoracic centers. These thymus fragments are used for the extraction of thymocytes to manufacture the medicine named Thymoglobuline. This medication is used in organ transplantation and in hematological disorders. THIS STUDY IS ENROLLING BY INVITATION ONLY - Subjects …
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HPP and Ehlers-Danlos Syndrome: Clinical Investigation

C
Clair Francomano
18 years - 65 years
All genders
Observational
What is the purpose of this study?The Ehlers-Danlos Syndromes (EDS) are a group of heritable disorders of connective tissue with joint hypermobility, chronic pain and a wide range of other conditions that overlap in symptoms including the musculoskeletal system, respiratory system, dental and neurologic issues. We think there may be …
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