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Found 684 results for in-health
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Molecular Analysis of Factors Involved in Benign Reproductive Tract Diseases
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Shannon Hawkins
What is the purpose of this study?The purpose of this study is to collect female reproductive tract tissues to investigate the key molecular events regulating endometriosis. Our central hypothesis is that by using well-characterized tissues, we can create novel models to improve treatments for endometriosis. THIS STUDY IS ENROLLING BY INVITATION …
HEALEY ALS Platform: Multi-Center, Multi-Regimen clinical trial evaluating investigational products for the treatment of ALS
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Cynthia Bodkin, MD
ALS is a degenerative disorder of the nerves controlling movement (“motor neurons”). ALS causes muscles to become weak, which leads to paralysis. ALS is a condition that gradually damages the nerve cells in the brain and spinal cord. Currently, there are no treatments to prevent, reverse, or stop the development of …
A Randomized Controlled Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy for the Management of Severe Open Tibia Fracture Wounds
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Yohan Jang
What is this study about?Open tibia fracture complications are debilitating for patients. NPWT is the current standard of care for temporary wound management of severe open fractures requiring multiple debridements. Emerging comparative studies suggest that the antibiotic bead pouch may significantly reduce the risk of open fracture infection and its …
Repair and Reconstruction of Scapholunate Ligament Injuries.
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Brian Christie
This study aims to compare patient outcomes from using different surgical techniques to treat scapholunate ligament (SLIL) injury (AIM 1); and to evaluate the effect of injury characteristics (chronicity, stage; AIM 2) on these outcomes.
Sympathetic Nerve Activity and Cardiovascular Events
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Thomas Everett
What is the purpose of this study?The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during supportive care for cardiac arrest, and to risk stratify patients for recurrence of atrial …
Microbiome alterations in the setting of intestinal failure associated liver disease
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Katie Huff
What is the purpose of this study?Neonates who require prolonged IV nutrition (TPN) are at risk for such complications as intestinal failure associated liver disease (IFALD). In addition, it is also known that TPN and lack of nutrition through the GI tract influences the intestinal microbiome or bacteria present in …
Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children
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Michael Hobson, MD
What is the purpose of this study?The overarching hypothesis of the ARRC trial is that administration of Azithromycin (AZM) during acute, Respiratory Syncytial Virus (RSV)-induced respiratory failure will be beneficial, mediated through the matrix metalloproteinase (MMP)-9 pathway. THIS STUDY IS ENROLLING BY INVITATION ONLY
A Global Multi-Center Prospective Observational Cohort to Support Drug Development in Adult Patients with Primary Sclerosing Cholangitis
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Craig Lammert, MD
What is the purpose of this study?To develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC. This is a Global, multi-center longitudinal observational cohort study. Collection of prospective clinical data to include liver-related clinical outcomes …
Role of neutrophil-specific NOX2 in alcohol-induced liver injury
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Suthat Liangpunsakul, MD
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
Parent Social Buffering and Dyadic Music Intervention to Decrease Distress in Infants and Young Children during Hematopoietic Stem Cell Transplant and their Parents
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Sheri Robb
The goal of the proposed study is to adapt an existing music-based intervention (Active Music Engagement; AME) using the ORBIT model, for infants and young children (3 years of age and under) undergoing stem cell transplant and their parents. Previous studies suggest that AME produces positive psychosocial outcomes for children …
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