Loading...
Found 685 results for in-health
A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Empagliflozin and Physical Function in CKD (EMPA-FUNCTION) Feasibility Study
K
Kenneth Lim
What is the purpose of this study?The purpose of the study is to assess the therapeutic benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors in improving physical function in End Stage Renal disease (ESRD) patients. The study is using the drug Empagliflozin, a FDA approved drug for patients with advanced CKD. …
Attenuating DEPression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors (ADEPT-ICU)
B
Babar Khan, MD
What is the purpose of this study?Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer’s disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with Internet CBT …
MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
N
Noel Dasgupta
What is the purpose of this study?To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM.
A Multi-Center, Prospective, Longitudinal, Study Evaluating Immunologic, Inflammatory, and Laboratory Parameters Associated With Long-Term Palynziq® (Pegvaliase) Treatment in Subjects With Phenylketonuria (PKU) in the United States
M
Melissa Lah, MD
This is a 10-year multi-center, prospective, longitudinal, single arm study evaluating immunologic, inflammatory and laboratory parameters associated with long-term Palynziq treatment in subjects with phenylketonuria (PKU) in the United States (US). Subjects in the US for whom a clinical decision has been made that they will receive pegvaliase to treat …
A Randomized Phase 3 Trial of Fludarabine/Cytarabine/Gemtuzumab Ozogamicin With or Without Venetoclax in Children With Relapsed AML
S
Sandeep Batra, MD
A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin [GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with …
A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Patients With Graves' Disease
C
Cary Mariash, MD
This is a study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.The primary objective of this study is to evaluate the efficacy of IMVT-1402 versus placebo as assessed by T3 (total triiodothyronine [T3] or …
Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance
J
Joel Corvera, MD
An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subjects treated with GORE® TAG® Conformable Thoracic Stent Graft with ACTIVE CONTROL System as a part of routine clinical practice. This post-market registry for the GORE® TAG® Conformable Thoracic Stent …
Global Prospective Hemolytic Disease of the Fetus and Newborn Registry
H
Hiba Mustafa, MD
The purpose of the study is to prospectively evaluate treatment effectiveness and outcomes for alloimmunized pregnant participants and their corresponding fetuses, neonates, infants, and children at risk for HDFN in a real-world setting. This prospective registry enables the identification of risk factors, disease progression patterns, and treatment outcomes in ways …
Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)
M
Marissa Just
This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in children, and FHWT is the most common subtype. Previous large clinical trials have established treatment plans that are likely …
A Post-Authorization Safety Study (Pass) to Assess Long-Term Safety in Patients with Pompe Disease Treated with Avalglucosidase Alfa in the Real-World Setting: the Savant (Safety Assessment of Avalglucosidase Alfa as a Novel Treatment) Study
M
Melissa Lah, MD
This is an observational study with the aim of gathering safety information on avalglucosidase alfa treatment for Pompe disease. We will collect long term safety data and evaluate the important identified risk of infusion associated reactions (IARs) including hypersensitivity and anaphylactic reactions and the important potential risk of medication errors …
Please choose between Voice or SMS based delivery of verification code
or