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Found 573 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

An Open-label, Multicenter Trial to Assess the Safety and Tolerability of Lumateperone in the Treatment of Pediatric Patients With Schizophrenia or Bipolar Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Phase 3
Interventional
What is the purpose of this study?This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia or bipolar disorder. THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is enrolling patients with schizophrenia, including patients who have previously participated …
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A Prospective, Single-Arm Multi-Center Study of the HARMONIC 700, 5 mm Diameter Shears with Advanced Hemostasis in Pediatric Surgical Procedures (General) and Adult Surgical Procedures (General, Gynecological, Urological, and Thoracic)

T
Troy Markel, MD
110 years or below
All genders
Interventional
What is the purpose of this study?The main purpose of this study is to demonstrate acceptable performance and assess safety of the HARMONIC 700 Shears device in a post-market setting when used per the instructions for use in pediatric and adult surgical procedures.THIS STUDY IS ENROLLING BY INVITATION ONLY - …
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A Randomized Phase II Study of Letrozole Versus Observation in Patients with Newly Diagnosed Uterine Leiomyosarcoma

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
What is the purpose of this study?This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily. Translational Objectives: 1. To preliminarily assess IHC hormone receptor expression and correlation …
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MAGNITUDE: A Phase 3, Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

N
Noel Dasgupta
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM. 
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Establishing Readiness of Dental Professionals in Practice-Based Research and Inter-Professional Care: Longitudinal Clinical Study

T
Thankam Thyvalikakath
30 years - 100 years
Accepts healthy volunteer
Female
What is the purpose of this study?The purpose of this research is to compare a group of females aged 30 years and above with pre Sjögren’s Disease conditions (fibromyalgia, joint pain, and fatigue) with a group of females 30 years and above who do not have these conditions. To do …
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Pilot ex-vivo investigation of an experimental beta probe for assessment and guidance of prostate cancer resection

C
Clinton Bahler, MD
18 years - 100 years
All genders
68Ga-PSMA is a radiopharmaceutical used with PET imaging for the detection of prostate cancer under a compassionate IND in patients who have presented with biochemical failure. In this study, the use of 68Ga-PSMA-11 will be extended to newly diagnosed patients with high risk prostate cancer. Patients enrolled to this study …
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A Multicenter Double Blind Placebo Controlled Study to Assess the Efficacy and Safety of H.P. Acthar? Gel in the Treatment of Subjects With Amyotrophic Lateral Sclerosis

C
Cynthia Bodkin, MD
18 years - 75 years
All genders
The purpose of this study is to determine if adding Acthar to riluzole will further help by either slowing down how fast ALS symptoms progress and/or increasing the time before you die.
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A Phase 3 Open-label Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Tezacaftor in Combination With Ivacaftor in Subjects With Cystic Fibrosis Aged 6 Years and Older Homozygous or Heterozygous for the F508del-CFTR Mutation

C
Clement Ren, MD
6 years - 100 years
All genders
The purpose of this study is to evaluate the long-term safety and tolerability of TEZ/IVA in subjects with cystic fibrosis aged 6 years and older, who are homozygous or heterozygous for F508del mutation.
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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Program toEvaluate the Efficacy and Safety of Tulisokibart in Participants with Moderately to SeverelyActive Crohn's Disease

M
Monika Fischer, MD
16 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. The protocol consists of 2 studies. Study 1 includes induction and maintenance treatment, and Study 2 includes only induction treatment. Each study …
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Comparative Effectiveness of Interventions to Improve Screening Among Rural Women

V
Victoria Champion
50 years - 74 years
Female
The purpose of this study is to compare the effectiveness of a tailored interactive DVD (TIDVD) vs telephone patient navigation (PN) + tailored interactive DVD (TIDVD) vs Usual Care in increasing screening rates for Breast Cancer (BC), Cervical Cancer (CC), and colorectal cancer (CRC) among women 50 -74 years living …
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