A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. Interested in participating? For more …
This study investigates the effects of adding an investigational medication, cemiplimab, to the usual treatment of docetaxel and ramucirumab for patients with stage IV or recurrent non-small cell lung cancer. This type of lung cancer is advanced and may have returned after previous treatment. Cemiplimab is a monoclonal antibody that …
This study investigates Huntington's disease (HD), a condition that affects the brain and causes movement, cognitive, and psychiatric disorders. The purpose of this study is to gather data on people with HD and their family members to better understand the disease. An observational study is a type of research study …
What is the purpose of this study?Duchenne muscular dystrophy (DMD) is a devastating X-linked disease which leads to loss ofbulation between ages 7 and 13, respiratory failure and cardiomyopathy (CM) at any age, an dvitably premature death of affected young men in their late twenties. DMD is the mostgenetic disorder …
Cholestasis is a condition in which bile is not properly transported from the liver to the. Cholestasis can be caused by an array of childhood diseases, including the genetic diseases Alagille syndrome (ALGS), alpha-1 antitrypsin (a-1AT) deficiency, bile acidynthesis and metabolism defects, and progressive familial intrahepatic cholestasis (PFIC) or benign …
The purpose of this study is to test the Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) among pregnant women (and their significant others) who are hospitalized for a potential periviable (early premature) delivery. We will evaluate the Periviable GOALS decision Support Tool's effects on shared …
This study investigates the differences between two dialysis access methods in female patients with end-stage renal disease (ESRD) who need hemodialysis. The purpose is to compare catheter-free days and infection severity between patients using two different types of access methods over 12 months.Participants will be randomly assigned to one of …
What is the purpose of this study?The purpose of this study is to test the hypothesis that skin sympathetic nerve activity (SKNA) can be used as a biomarker for physiological events including predicting neurological recovery during supportive care for cardiac arrest, and to risk stratify patients for recurrence of atrial …
What is the purpose of this study?NADPH oxidase 2 (NOX2) is the isoform of NOX found in phagocytes including neutrophils, NOX2 activation generates reactive oxygen species (ROS) with antimicrobial activities. Patients with advanced alcoholic cirrhosis or alcoholic hepatitis are more susceptible to infections due to deficient ROS production by neutrophils. …
What is the purpose of this study?PREVENT ALL ALS is a prospective, observational cohort study enrolling individuals at risk for carrying inherited genetic variants known to be causative for ALS. This is a longitudinal observational study involving collection of clinical data, outcomes andbiofluid samples. There is also an optional sub-study …
