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Found 65 site-public-contact trials

A listing of site-public-contact medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Randomized Phase II Trial of Doxorubicin + Pembrolizumab Versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas

S
Samantha Armstrong
18 years - 100 years
All genders
Phase 2
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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A Phase 3, Randomized, Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma

R
Rafat Abonour, MD
18 years - 100 years
All genders
Phase 3
What is the purpose of this study?The goal of this study (iMMagine-3) is to compare the study drug, anitocabtagene autoleucel to standard of care therapy (SOCT) in participants with relapsed/refractory multiple myeloma who have received 1 to 3 prior lines of therapy, including an anti-CD38 monoclonal antibody and an immunomodulatory …
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Study of a Treatment Being Studied for Advanced Tumors and Lymphoma

R
Rohan Maniar
18 years - 100 years
All genders
Phase 1/2
This study investigates the use of an investigational medication in adults with advanced solid tumors or non-Hodgkin lymphoma (NHL). The purpose is to learn about the safety and effects of different doses and ways of giving the medication. Solid tumors are abnormal masses of tissue that can be cancerous, and …
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Study on Medication for Appetite Loss in Cancer

S
Susan Ballinger
18 years - 100 years
All genders
Phase 3
This study investigates the effects of an investigational medication on appetite loss in patients with advanced cancer. Advanced cancer means the cancer has spread to other parts of the body. The purpose of this study is to compare the investigational medication with another usual medication to see which one is …
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Investigating a Combination Therapy for Advanced Breast Cancer

K
Kathy Miller, MD
18 years - 100 years
All genders
Phase 1
This study investigates the safety and effects of a combination treatment for locally advanced or metastatic breast cancer. Breast cancer is a disease where cells in the breast grow out of control. This study looks at an investigational medication made from the patient's own T cells, which are a type …
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Research Study for Muscle-Invasive Bladder Cancer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2
This study investigates muscle-invasive bladder cancer, a type of cancer that grows into the muscle layer of the bladder. The purpose is to see how well an investigational medication combined with another treatment works for this type of cancer. The study involves patients with muscle-invasive bladder cancer receiving treatment and …
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A Randomized Phase III Study to Evaluate Benefits of Autologous Stem Cell Transplant in Patients with Peripheral T Cell Lymphoma that Achieved a First Complete Remission (CR1) Following Induction Therapy (PTCL-STAT)

U
Utpal Dave, MD
18 years - 75 years
All genders
Phase 3
Primary: To demonstrate improvement in progression free survival (PFS) in the autologous stem cell transplant (ASCT) arm compared to the observation arm. Secondary: -To assess difference in overall survival (OS) between the observation and autologous stem cell transplant (ASCT) arm. -To evaluate the differences in study intervention benefit for PFS …
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Study on Safety and Tolerability of Investigational Medication in Advanced Solid Tumors (types of cancer that form solid masses)

N
Nabil Adra, MD
15 years - 100 years
All genders
Phase 1
This study investigates the safety and tolerability of an investigational medication in people with advanced solid tumors. Advanced solid tumors are cancers that have spread and are difficult to treat. The purpose of this study is to find out if the investigational medication is safe and to determine the best …
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Research on Medicine for Pancreatic and Lung Cancer

A
Anita Turk, MD
18 years - 100 years
All genders
This study investigates the safety and effects of an investigational medication in combination with other agents for patients with pancreatic or non-small cell lung cancer. These cancers are being studied because they have specific genetic changes called MTAP loss and RAS mutation. The purpose is to see how the investigational …
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Investigating the Safety of an Investigational Treatment for a Type of Cancer Affecting White Blood Cells

H
Huda Salman
18 years - 100 years
All genders
Phase 1
This study investigates the safety of an investigational treatment using special immune cells called CAR-T cells for people with certain B cell cancers. B cell malignancies are cancers that affect a type of white blood cell. The study includes participants whose cancer has returned or not responded to previous treatments. …
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