Found 147 results for Neoplasm
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Examining Genetic Ancestry, Allostatic Load and Treatment Completion among Patients with Breast Cancer
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Tarah Ballinger, MD
The main purpose of this study is to learn more about how genetic ancestry affects treatment completion for patients who are diagnosed with breast cancer. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: …
Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy
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Namita Agrawal
The purpose of this study is to examine the feasibility of adding pre-rehabilitation pelvic health physical therapy to standard of care radiation therapy treatment plan for female patients who have been diagnosed with cervical, vaginal, vulvar, uterine, or anal cancer and are a candidate for curative pelvic radiation with external …
NearWave optical molecular monitoring for predicting complete pathological response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer patients
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Tarah Ballinger, MD
The purpose of this study is to assess the feasibility of the NearWave optical molecular monitoring system for monitoring therapy progression and predicting pathologic complete response (pCR) of breast cancer patients undergoing neoadjuvant chemotherapy (NAC). Interested in participating? For more information about this research study or other cancer-related clinical trials at …
A Phase II Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiationfor the Treatment of Early-Stage Anal Cancer
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Anita Turk, MD
Primary Objective:1. To determine the clinical complete response rate (cCR) assessed following weekly carboplatin and paclitaxel in combination with pembrolizumab and radiation for the treatment of early-stage anal cancer. Secondary Objectives:1. To assess the safety and tolerability of weekly carboplatin and paclitaxel in combination with pembrolizumab and radiation for the treatment …
A Phase 3, Open-label, Multicenter, Randomized Trial of TrastuzumabDeruxtecan with Bevacizumab Versus Bevacizumab Monotherapy asFirst-line Maintenance Therapy in HER2-Expressing Ovarian Cancer.
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Jessica Parker
This clinical trial is designed to evaluate the efficacy and safety of T-DXd in combination with bevacizumab versus bevacizumab monotherapy as first-line maintenance therapy, in participants with human epidermal growth factor 2 (HER2)-expressing (immunohistochemistry [IHC] 3+/2+/1+) advanced high-grade epithelial ovarian cancer.Interested in participating? For more information about this research study …
A Prospective Low-Interventional Phase 4 Single Arm Study of Ocular Assessments in Patients Treated with Tivdak® in Recurrent or Metastatic Cervical Cancer
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Sharon E. Robertson
TIVDAK is used for the treatment of cervical cancer that has come back after chemotherapy. Chemotherapy is a treatment that uses medicines to stop the growth of cancer cells. This is done either by killing the cells or by stopping them from growing. The purpose of this study is to …
Evaluating Financial Barriers to Breast Cancer Patients Participating in Clinical Trials
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Kathy Miller, MD
The purpose of this study is to understand the indirect costs (i.e., lost income, travel costs, parking costs, etc.) taken on by breast cancer patients who have enrolled in cancer clinical trials.Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive …
Shortstop-Her2: Shortened Duration of Adjuvant Therapy in Patients with Early-Stage Her2+ Breast Cancer Who Achieve Pcr After Neoadjuvant Chemotherapy with Her2 Blockade
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Kathy Miller, MD
This phase III trial compares 6 months of human epidermal growth factor receptor 2 (HER2)-targeted therapy to 12 months of HER2-targeted therapy for the treatment of HER2-positive (+) breast cancer in patients that had a pathologic complete response (pCR) after preoperative (neoadjuvant) chemotherapy with trastuzumab. Trastuzumab and pertuzumab are monoclonal …
A Randomized, Active-Controlled, Double-Blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with Folfox Versus Bevacizumab in Combination with Folfox for the First-Line Treatment of Metastatic Colorectal Cancer
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Anita Turk, MD
Primary ObjectiveTo compare the progression-free survival (PFS) as assessed by blinded Independent. Radiological Review Committee (IRRC) based on Response Evaluation Criteria in. Solid Tumors (RECIST) v1.1, of ivonescimab in combination with modified 5-FU, oxaliplatin, and leucovorin (mFOLFOX6) to bevacizumab in combination with mFOLFOX6.Secondary ObjectivesTo compare the overall survival (OS) of …
The Susan G Komen Tissue Bank at the IU Simon Cancer Center A Collection and Storage of Biological Specimens Intended for use in the Elucidation of Breast Carcinogenesis
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Michele Cote
Would you like to contribute to the fight against breast cancer? You can help by donating a breast tissue sample during an event at the IU Melvin and Bren Comprehensive Cancer Center from 8 am to 2 pm on October 19th, 2024. While the donation process takes only 60-90 minutes, …
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