Found 147 results for Neoplasm
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
PATIENTS PERSPECTIVES ON TREATMENT DECISION-MAKING AND THE ACCEPTABILITY AND USABILITY OF THE INTERACTIVE WEB-ENABLED COMMUNICATION RESOURCES OF THE CLL/SLL CARE ROAD MAP
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Larry Cripe, MD
The purpose of the study is to understand how people think about choosing between two or more treatment options and then to seek their reactions to the CLL Mind Map and Patient First Resources. Interested in participating? For more information about this research study or other cancer-related clinical trials at Indiana …
A Randomized Phase Ii Study of Venetoclax and Hma-Based Therapies for the Treatment of Older and Unfit Adults with Newly Diagnosed Flt3-Mutated Acute Myeloid Leukemia (Aml): A Myelomatch Treatment Trial
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Rita Assi
This phase II MyeloMATCH treatment trial compares the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib in treating older and unfit patients with acute myeloid leukemia and FLT3 mutations. Azacitidine is a drug that is absorbed into DNA and leads to the activation …
A Randomized, Open-Label Study Evaluating The Efficacy And Safety Of Cemacabtagene Ansegedleucel In Participants With Minimal Residual Disease After Response To First Line Therapy For Large B-Cell Lymphoma (Alpha3)
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Varun Mittal
This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved a complete response or partial response suitable for observation, but who have minimal residual disease (MRD) as detected by the Foresight CLARITY™ Investigational Use Only (IUO) MRD …
Randomized, Open-Label Study of the Bria-Imt Regimen and Check Point Inhibitor Vs Physician S Choice in Advanced Metastatic Breast Cancer (Bria-Abc)
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Tarah Ballinger, MD
The purpose of this study is to evaluate the effect of the Bria-IMT regimen in combination with Check Point Inhibitor (CPI) on overall survival (OS) compared to treatment of physician’s choice (TPC) chemotherapy in patients with metastatic breast cancer with no approved alternative therapies available as per the Inclusion criter …
A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy of Cemsidomide + Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma
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Attaya Suvannasankha, MD
The purpose of this Phase 2 study is to assess the antimyeloma activity and further characterize the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of cemsidomide in combination with dexamethasone in subjects with relapsed/refractory multiple myeloma (r/r MM).Interested in participating? For more information about this research study or other cancer-related …
A PHASE III TRIAL OF THE IMPACT OF SENTINEL LYMPH NODE MAPPING ON PATIENT REPORTED LOWER EXTREMITY LIMB DYSFUNCTION IN ENDOMETRIAL CANCER
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Lisa Landrum, MD, PhD, MS
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy …
Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
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Lisa Landrum, MD, PhD, MS
This phase II/III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy …
Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer
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Tim Lautenschlaeger
There has been evidence that patients being treated with chemoradiation for Non-Small Cell Lung Cancer (NSCLC) have experienced cardiac toxicities (heart damage). This study is exploring if testing patients hearts that have been diagnosed with NSCLC before and after treatment can help investigators decrease heart damage for patients in the …
Exploring Treatment Options After Lung Cancer Surgery
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Vijaya L. Kakani, MD
Do you have non-small cell lung cancer (NSCLC) but the cancer was not fully removed by surgery? You may qualify for a study exploring treatment options for NSCLC.This research study is testing whether adding a medication called sacituzumab tirumotecan to pembrolizumab after surgery may help prevent non-small cell lung cancer …
PSMAcTION: A phase II/III, open-label, international, multi-center, randomized study of AAA817 versus standard of care in the treatment of adult participants with PSMA-positive metastatic castration-resistant prostate cancer who progressed on or after [177Lu]Lu-PSMA targeted therapy.
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Nabil Adra, MD
This is a Phase II/III study. Patient population is adult participants with PSMA-positive mCRPC who had treatments with androgen receptor pathway inhibitor (ARPI) and taxane-based chemotherapy and progressed on or after [177Lu]Lu-PSMA targeted therapy.Treatment of interest: the investigational treatment is AAA817 regardless of subsequent anti-neoplastic treatment. The control treatment is …
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