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Found 151 Neoplasm trials
A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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Tareq Salous
This study investigates how well an investigational medication combination works in treating adults with untreated locally advanced or metastatic urothelial carcinoma with an FGFR3 genetic alteration. Urothelial carcinoma is a type of cancer that occurs in the urinary system. This study uses a combination of medications, including monoclonal antibodies, which …
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Tarah Ballinger, MD
This study investigates the effect of low-dose aspirin on inflammation markers in postpartum patients with benign breast disease. Postpartum refers to the period after childbirth. Chronic inflammation may increase the risk of developing breast cancer after having a baby. Low-dose aspirin is a type of medication that reduces inflammation and …
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Rohan Maniar
What is the purpose of this study?This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer. Amivantamab-SC is a drug that reduces extra copies of the MET gene, a change present in your tumor. Giving amivantamab-SC …
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Jennifer King
This study investigates treatments for advanced clear cell renal cell carcinoma, a type of kidney cancer. The purpose of this study is to compare the effects of an investigational medication combined with cabozantinib versus a placebo combined with cabozantinib. Participants in this study have advanced or metastatic clear cell renal …
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Sharon E. Robertson
This study investigates treatment options for high risk locally advanced cervical cancer, where the cancer has spread to nearby tissues or lymph nodes. The study compares two approaches: one with induction chemotherapy using an investigational medication and chemotherapy, followed by chemoradiation and maintenance therapy, and the other with just chemoradiation …
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Utpal Dave, MD
This study investigates the potential benefits of using high dose chemotherapy followed by a patient's own stem cells, known as an autologous stem cell transplant, in treating peripheral T-cell lymphoma. Peripheral T-cell lymphoma is a type of cancer that affects T-cells, which are part of the body's immune system. The …
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Samantha Armstrong
What is the purpose of this study?This phase II trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started to other places in the …
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Angela M. Richardson, MD, PhD
What is the purpose of this study?The purpose of this study is to look at the effect of oxygen on tumor tissue and cerebrospinal fluid(CSF). Tissue in your body is exposed to less oxygen than is in the air around you. Traditional studies use cells and tissue kept in room …
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Anna Maria Storniolo, MD
What is the purpose of this study?Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center and at participating sites will be entered onto this tissue procurement protocol for …
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April Rahrig, MD
This study investigates the use of an investigational medication to prevent cytomegalovirus (CMV) infection in children and adolescents who have undergone a stem cell transplant. Cytomegalovirus is a virus that can cause infections, especially in people with weakened immune systems. "Prophylaxis" means taking a drug to prevent a disease or …
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