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Found 645 IU Health Enterprise System trials

A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Comparing Surgical and Non-Surgical Treatments for Pelvis Fractures

Y
Yohan Jang
60 years - 100 years
All genders
Interventional
This study investigates the effectiveness of early surgical treatment compared to non-surgical care with early rehabilitation for pelvis fractures. A pelvis fracture is a break in one or more of the bones of the pelvis. The study focuses on patients aged 60 years or older with a specific type of …
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Clinical Trial Designed to Assess the Safety and Effectiveness of the KOKO Device In Treating Primary Abnormal Postpartum Uterine Bleeding ("APUB") or Hemorrhage ("PPH")

C
Christina M. Scifres, MD
18 years - 100 years
Female
Interventional
What is the purpose of this study?The sponsor of this research study, KOKO Medical Inc, is evaluating a medical device to control and treat abnormal postpartum uterine bleeding or hemorrhage (excessive bleeding). The device is called the KOKO device and its use in this study is experimental. The purpose of …
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Study on Imaging Techniques for Prostate Cancer Surgery

C
Clinton Bahler, MD
18 years - 100 years
Male
This study investigates the use of a special scan called PSMA PET to guide surgery for prostate cancer. The purpose is to find out if the PSMA PET scan can better detect cancer near the edge of the prostate and help doctors plan the surgery. Prostate cancer is a disease …
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Comparative Analysis of Extracellular Vesicles in Polycystic Ovary Syndrome (PCOS), Congenital Adrenal Hyperplasia (CAH), and Premature Adrenarche (PA)

E
Erica Eugster, MD
M
Manahil Mustafa
3 years - 18 years
Female
Observational
What is the purpose of this study?Extracellular vesicles (EVs) are double-membrane particles that transport proteins, microRNAs (miRNAs), and lipids, playing a crucial role in cell-to-cell communication and reflecting the cellular environment. Recent research has highlighted their potential as biomarkers and therapeutic agents in various adult conditions, yet their role in …
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The Heart Outcomes in Pregnancy Expectations for Mom and Baby Study

C
Caroline Rouse, MD
18 years - 100 years
Female
Observational
This is a prospective, observational study which is evaluating the obstetrical, neonatal, and cardiovascular outcomes of 1000 pregnant people with known heart disease to define how best to structure cardio-obstetrics care to optimize outcomes.THIS STUDY IS ENROLLING BY INVITATION ONLY - This study is enrolling participants from specified community and …
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Investigational Medication for Chronic Kidney Disease and High Blood Pressure

S
Sharon Moe, MD
18 years - 100 years
All genders
Phase 3
Interventional
This study investigates how well an investigational medication works when combined with another medicine in people with chronic kidney disease (CKD) and high blood pressure (hypertension). CKD is a condition where the kidneys are damaged and can't filter blood as well as they should. Hypertension is when the blood pressure …
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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

J
Jonathan L. Berkowitz, MD, PhD
18 years or above
All genders
Interventional
This randomized research trial studies how well serum tumor marker directed disease monitoring works in monitoring patients with hormone receptor positive Her2 negative breast cancer that has spread to other places in the body. Using markers to prompt when scans should be ordered may be as good as the usual …
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Investigating Hematopoietic Stem Cell Transplantation in Non-Malignant Diseases

J
Jodi Skiles
20 years or below
All genders
This study investigates the use of Hematopoietic Stem Cell Transplantation (HSCT) in children with non-cancerous diseases. The purpose is to use a preparatory regimen that suppresses the immune system without destroying bone marrow to allow donor cells to engraft. The study aims to understand the main side effects of this …
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Study of Genetic Factors in Heart and Blood Vessel Diseases

L
Larry Markham
100 years or below
All genders
This study investigates the genetic causes of thoracic aortic aneurysm (TAA) and other aortic diseases. The purpose is to find new genes that may cause these conditions and understand how genetics can affect the severity of aortic and valve diseases.Participants will provide blood and urine samples. If blood samples cannot …
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Post-Traumatic Stress, Depression, and Anxiety Following Liver Transplantation

A
Archita Desai, MD
18 years - 100 years
All genders
Observational
The purpose of this study is to help understand the rates of psychosocial illness in liver transplant recipients and examine their health related quality of life (HR QOL) measures.
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