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Found 594 results for IU Health Enterprise System
A listing of IU Health Enterprise System medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
A Prospective Randomized Controlled Trial of Chronic Nausea and Vomiting in Patients With Normal Gastric Emptying Using the Enterra® Therapy System
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Thomas Nowak, MD
What is the purpose of this study?The purpose of this research study is to determine if the Enterra® Therapy System can decrease nausea and vomiting symptoms and improve the quality of life for patients with chronic nausea, with or without vomiting, that have normal gastric emptying. THIS STUDY IS ENROLLING BY …
A Phase III Trial of One vs. Two Years of Maintenance Olaparib, with or without Bevacizumab, in Patients with BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy
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Jessica Parker Metter
What is the purpose of this study?This phase III trial compares the effect of olaparib for one year versus two years, with or without bevacizumab, for the treatment of BRCA 1/2 mutated or homologous recombination deficient stage III or IV ovarian cancer. Olaparib is a polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme …
Sample Collection to Assess Physioxia in Brain Tumors
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Angela M. Richardson, MD, PhD
What is the purpose of this study?The purpose of this study is to look at the effect of oxygen on tumor tissue and cerebrospinal fluid(CSF). Tissue in your body is exposed to less oxygen than is in the air around you. Traditional studies use cells and tissue kept in room …
Personality traits and induced laryngeal obstruction
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Robert Fujiki
What is the purpose of this study?Paradoxical Vocal Fold Movement (PVFM; also called Induced Laryngeal Obstruction [ILO]) consists of vocal fold adduction which occurs upon inspiration and results in dyspnea. The etiology of PVFM is often multifactorial and varied across patients. PVFM has been categorized in the literature based on …
A Randomized Phase 1/2 Trial of Low Dose Anti-Thymocyte Globulin (Atg) with Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes (Wave T1D)
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Hannah Lease
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Linda DiMeglio, MD
The purpose of this study is to learn if a low dose of a medication called ATG, combined with either Adalimumab or Verapamil, can help the pancreas continue to make insulin for a longer time which may also help to control blood glucose. This multi-center randomized controlled trial will assess …
Novel Use of Combined High-Speed Video Microscopy and Nasal Nitric Oxide Screening for Identification of Primary Ciliary Dyskinesia in Adult Bronchiectasis
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Mike Davis
Bronchiectasis is a chronic respiratory disease characterized by irreversible airway damage and recurrent infection, and many patients remain without an identifiable cause even after standard testing. Primary ciliary dyskinesia (PCD), a genetic disorder that causes bronchiectasis due to defecttive mucus clearance in the lungs, is substantially underdiagnosed in adult bronchiectasis …
A Phase 3, Open-Label, Multicenter, Single-Arm Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Dulaglutide 3.0 Mg and 4.5 Mg in Pediatric Participants 10 to Less Than 18 Years of Age With Type 2 Diabetes Mellitus
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Tamara Hannon, MD
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of dulaglutide 3.0 mg and 4.5 mg in pediatric participants 10 to less than 18 years of age with T2DM.THIS STUDY IS ENROLLING BY INVITATION ONLY
A Pilot Study in the Treatment of Refractory Epstein-Barr Virus (EBV) Infection with Related Donor EBV Cytotoxic T-Lymphocytes in Children, Adolescents and Young Adult Recipients - NYMC 581
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Scott Goebel, MD
What is the purpose of this study?Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured withhe Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children,dolescents and young adults with refractory EBV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid …
Prospective Validation of a Points Score System Predicting 30-day Survival
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Naoyuki Saito, MD
What is the purpose of this study?This is a one-stage single-arm phase II clinical trial designed to prospectively test the survival prediction tool as developed by Lee et al on patients referred to radiation oncologyve treatments. Survival prediction score based on objective data includingboratory values, attendance to emergency room, and …
Reactive Oxygen Species in Respiratory Failure, Delirium, and Post-ICU Cognitive Impairment
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Sikandar Khan, MD
The purpose of this study is to better understand the relationship between being ill and the release of chemicals that go up with stress using blood samples. We will also measure physical and mental recovery of patients after being admitted to the Intensive Care Unit (ICU).
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