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Found 585 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A
Angela M. Richardson, MD, PhD
18 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?This trial will be a randomized controlled study comparing the efficacy and safety ofve radiation therapy using GammaTilesTM (GT) versus SRS 3-4 weeks followingumor resection which is the current standard of care. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
N
Naoyuki Saito, MD
50 years - 70 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III Trial evaluates whether breast conservation surgery and endocrine therapyults in a non-inferior rate of invasive or non-invasive ipsilateral breast tumorurrence (IBTR) compared to breast conservation with breast radiation and endocrineherapy.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology …
S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured withhe Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children,dolescents and young adults with refractory EBV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid …
S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Captureystem will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary …
S
Scott Coven
1 year - 25 years
All genders
Phase 1
Interventional
What is the purpose of this study?This phase I trial studies the side effects and best dose of trametinib and everolimus ing pediatric and young adult patients with gliomas that have come back (recurrent). Trametinib acts by targeting a protein in cells called MEK and disrupting tumor growth.verolimus is a …
B
Brian Weiss
12 months - 30 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits ofgavivint in treating patients with solid tumors that has come back (recurrent) or does notd to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help …
S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with theyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in inhildren, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) ord organ …
S
Scott Goebel, MD
1 month - 30 years
All genders
Phase 2
Interventional
What is the purpose of this study?CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ …
J
Jenny Belsky, DO
2 years or above
All genders
Phase 3
Interventional
What is the purpose of this study?This phase III trial compares the effects of nivolumab with chemo-immunotherapy versushemo-immunotherapy alone in treating patients with newly diagnosed primary mediastinal B-cell lymphoma (PMBCL). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with …
B
Brian Weiss
12 years - 39 years
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to …
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