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Found 704 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Pilot Study in the Treatment of Refractory Epstein-Barr Virus (EBV) Infection with Related Donor EBV Cytotoxic T-Lymphocytes in Children, Adolescents and Young Adult Recipients - NYMC 581

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Epstein-Barr Virus (EBV) specific cytotoxic T cells (CTLs) manufactured withhe Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children,dolescents and young adults with refractory EBV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid …
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Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 1/2
Interventional
What is the purpose of this study?BK cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Captureystem will be safe and effective in decreasing specific viral load in children, adolescents and young adults (CAYA) with refractory BK infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary …
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Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

S
Scott Goebel, MD
1 month - 79 years
All genders
Phase 2
Interventional
What is the purpose of this study?Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with theyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in inhildren, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) ord organ …
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Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)

S
Scott Goebel, MD
1 month - 30 years
All genders
Phase 2
Interventional
What is the purpose of this study?CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ …
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A Randomized, Double-blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

P
Phuongthao Quan
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of XEN1101 administered as adjunctive treatment in adult subjects diagnosed with generalized epilepsy and experiencing probable or possible PGTCS (with or without other subtypes of generalized …
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A PHASE 2, TWO-STAGE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTIPLE-ASCENDING DOSE STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PRELIMINARY EFFICACY OF RLS-0071 IN NEWBORNS WITH MODERATE OR SEVERE HYPOXIC-ISCHEMIC ENCEPHALOPATHY UNDERGOING THERAPEUTIC HYPOTHERMIA WITH LONG-TERM FOLLOW-UP

B
Beatrice Stefanescu
10 hours or below
All genders
Phase 2
Interventional
What is the purpose of this study?Hypoxic-ischemic encephalopathy (HIE) affects approximately 4,000 to 12,000 persons annually in the United States. Mortality from HIE has been reported up to 60%, with at least 25% of survivors left with significant neurocognitive disability. Despite this vital unmet medical need, no pharmacological adjunct or …
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Crohn's Disease: Pharmacokinetics, Efficacy, and Safety of Risankizumab in Pediatric Subjects with Moderately to Severely Active Crohn's Disease

T
Tina Zhang
2 years - 18 years
All genders
Interventional
What is this study about?The objective of this study is to assess the pharmacokinetics (PK), efficacy, and safety of risankizumab in pediatric subjects with moderately to severely active CD aged 2 to < 18 years old who have had intolerance or inadequate response to aminosalicylates, oral locally acting corticosteroids, systemic …
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A Multicenter, Open-label, Long-term, Safety, Tolerability, and Efficacy Study of XEN1101 in Adults Diagnosed With Epilepsy

P
Phuongthao Quan
18 years - 100 years
All genders
Interventional
What is the purpose of this study?To assess the safety and tolerability of XEN1101. Percent change in monthly seizure rate recorded at baseline (in the antecedent studies) compared to each 4-week assessment period in the treatment period in X-TOLE4.THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants must have successfully …
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A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Determine the Safety and Efficacy of Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

D
Damien G. Patel, MD
40 years - 100 years
All genders
Phase 2
Interventional
What is the goal of this study?Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The purpose of this study is to determine the safety and efficacy of oral ifetroban compared to placebo in subjects with IPF. THIS STUDY IS ENROLLING BY INVITATION ONLY  
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Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta

J
Joel Corvera, MD
18 years - 100 years
All genders
Interventional
What is this study about?The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch. THIS STUDY IS ENROLLING BY INVITATION ONLY
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