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Found 706 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Randomized, Double-Blind, Placebo-Controlled Phase II Study to Determine the Safety and Efficacy of Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

D
Damien G. Patel, MD
40 years - 100 years
All genders
Phase 2
Interventional
What is the goal of this study?Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The purpose of this study is to determine the safety and efficacy of oral ifetroban compared to placebo in subjects with IPF. THIS STUDY IS ENROLLING BY INVITATION ONLY  
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Evaluation of the GORE® Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta

J
Joel Corvera, MD
18 years - 100 years
All genders
Interventional
What is this study about?The primary objective of ARISE II is to assess the safety and effectiveness of the GORE® Ascending Stent Graft device in the treatment of lesions involving the ascending aorta and aortic arch. THIS STUDY IS ENROLLING BY INVITATION ONLY
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AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansion

R
Raghu Motaganahalli, MD
18 years - 100 years
All genders
Interventional
Why is this study being done?To determine the safety and effectiveness of IMPEDE-FX RapidFill to improve AAA sac behavior when used with EVAR stent graft treatment. THIS STUDY IS ENROLLING BY INVITATION ONLY
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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of Fazirsiran in the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease With METAVIR Stage F1 Fibrosis

R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Phase 3
Interventional
Why is this study being done?In some people, the liver makes an abnormal version of the alpha-1 antitrypsin (AAT) protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver …
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Study on Vascular Stent for Leg Artery Blockages

G
Greg Westin
18 years - 100 years
All genders
Interventional
This study investigates the safety and effectiveness of an investigational vascular stent system for treating peripheral artery disease. Peripheral artery disease is a condition where the arteries in the legs become narrowed or blocked, which can cause pain and other symptoms. The investigational stent will be used to treat blockages …
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A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)

A
Ankit Desai
18 years - 85 years
All genders
Phase 3
Interventional
What is the purpose of this study?The study will evaluate the efficacy and safety of chronic oral levosimendan compared with placebo in PH-HFpEF subjects. This subject population represents a large and growing group with no established therapies to treat their PVD and RV dysfunction. Levosimendan and its prolonged active metabolite, …
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An open-label, phase II proof-of-concept study to evaluate the clinical efficacy and safety of tapinarof for adult patients with palmoplantar keratoderma

D
David Rosmarin
18 years - 75 years
All genders
Phase 2
Interventional
What is the purpose of this study?This study is being done to find out how safe and how well the drug Tapinarof (VTAMA) works for stopping or treating palmoplantar keratoderma, which is a condition characterized by thickened skin on your palms and soles.  Tapinarof, used as a topical 1% cream, …
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Inhibition of Small Conductance Calcium-Activated Potassium Current: A New Therapeutic Approach for Atrial Fibrillation

J
James Tisdale
18 years - 100 years
All genders
Interventional
What is the purpose of this study?Atrial fibrillation/ atrial flutter are common irregular heart beats or arrhythmias that causes quivering of the heart and sometimes a very fast heart rate and can lead to blood clots and strokes. Many of the current drugs on the market used to treat atrial …
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Study on Preparation Therapy for Women Undergoing Pelvic Radiotherapy

N
Namita Agrawal
18 years or above
Female
Interventional
This study investigates the feasibility of adding pre-rehabilitation pelvic health physical therapy to the standard radiation treatment plan for women with certain types of cancer. These include cervical, vaginal, vulvar, uterine, or anal cancer. Participants will receive education on using a vaginal dilator during their treatment. The study will also …
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DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

M
Michael Ferguson, MD
25 years or below
All genders
Phase 3
Interventional
What is the purpose of this study?This is a 2-arm, randomized, open-label, multicenter, global, Phase 3 trial to evaluate the efficacy, safety, and tolerability of tovorafenib monotherapy versus standard of care (SoC) chemotherapy in patients with pediatric low-grade glioma (LGG) harboring an activating rapidly accelerated fibrosarcoma (RAF) alteration requiring front-line …
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