A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to …
What is the purpose of this study?This is an open label randomized phase II trial of maintenance oral etoposide vs. observationwith relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood(PBSCT).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients are not actively “recruited,” but are screened …
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
What is this study about?The objective of this study is to assess the pharmacokinetics (PK), efficacy, and safety of risankizumab in pediatric subjects with moderately to severely active CD aged 2 to < 18 years old who have had intolerance or inadequate response to aminosalicylates, oral locally acting corticosteroids, systemic …
What is this study about?The PERFORMANCE III study is a prospective, multicenter single-arm, open label study to evaluate the safety and effectiveness of the Neuroguard IEP® Direct System for the treatment of carotid artery stenosis in subjects at elevated risk for carotid endarterectomy (CEA).Eligible patients greater than or equal to …
What is the purpose of this study?The purpose of this study is to study exercise in a novel population with indolent MBC (nogression on current therapy in prior 12 months and not receiving cytotoxic chemotherapy). The study team hypothesizes that delivering virtual, supervised, progressive intensitybic and resistance training exercise for …
What is the purpose of this study?This phase III trial compares hematopoietic (stem) cell transplantation (HCT) usinghed related donors (haploidentical [haplo]) versus matched unrelated donors (MUD) ing children, adolescents, and young adults with acute leukemia or myelodysplasticyndrome (MDS). HCT is considered standard of care treatment for patients with high-riskute leukemia …
What is the purpose of this study?To assess the safety and tolerability of XEN1101. Percent change in monthly seizure rate recorded at baseline (in the antecedent studies) compared to each 4-week assessment period in the treatment period in X-TOLE4.THIS STUDY IS ENROLLING BY INVITATION ONLY - Participants must have successfully …
What is the goal of this study?Ifetroban prevents and treats lung fibrosis due to multiple causes (bleomycin, genetic, radiation). The purpose of this study is to determine the safety and efficacy of oral ifetroban compared to placebo in subjects with IPF. THIS STUDY IS ENROLLING BY INVITATION ONLY
