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Found 697 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Safety and Effects of Investigational Antibiotic in Infants

A
Anna Elizabeth Thomas
9 months or below
All genders
Phase 1/2
Interventional
This study investigates the safety and effects of an investigational medication for treating infections caused by gram-negative bacteria in newborns and infants. Gram-negative bacteria are a type of bacteria that can cause various infections and are known for their resistance to antibiotics. The investigational medication is a combination of two …
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Investigating the Safety and Effects of an Investigational Medication in Children with ANCA-associated Vasculitis

S
Stacey Tarvin, MD
6 years - 17 years
All genders
Phase 3
Interventional
This study investigates the safety and effects of an investigational medication combined with a regimen containing either rituximab or cyclophosphamide in children with ANCA-associated vasculitis (AAV). ANCA-associated vasculitis is a condition where the body's immune system mistakenly attacks blood vessels, causing inflammation. The study focuses on children aged 6 to …
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OnX Liver Assessment Solution Clinical Study

R
Raj Vuppalanchi, MD
22 years - 80 years
All genders
Interventional
What is the purpose of this study?This protocol’s primary aim is to assess the performance of the OnX exam on patients with suspected or confirmed liver disease with the goal of comparing the OnX output stiffness estimates to FibroScan® liver stiffness measurements. Our primary objectives are to assess whether the …
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Study on Investigational Medication for X-linked Hypophosphatemia (XLH)

E
Erik Imel, MD
18 years - 65 years
All genders
Phase 1/2
Interventional
This study investigates the safety and effectiveness of an investigational medication for adults with X-linked hypophosphatemia (XLH). XLH is a rare genetic disorder that affects the bones and teeth, leading to low levels of phosphate in the blood, which can cause bone pain and deformities. The study is open-label, meaning …
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Supplementation of Skeletal Survey with Whole Body MRI for Fracture Detection in Children with Suspected Physical Abuse

C
Christopher Newman
2 years or below
All genders
Interventional
What is the purpose of this study?Children with a skeletal survey for suspected physical abuse who are already receiving MR imaging for possible neurological injuries will be imaged with additional whole body MRI. They will also receive a clinical follow up skeletal survey, which will serve as the reference standard …
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Denosumab for Type 1 Diabetes

C
Carmella Evans-Molina, MD
18 years - 50 years
All genders
Phase 1/2
Interventional
Researchers at City of Hope (California), University of Alabama at Birmingham, and Indiana University are studying a medication called denosumab as a potential treatment for people with type 1 diabetes. Denosumab, also known as Prolia, is a drug that has been approved by the Food and Drug Administration for bone …
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Study on Preventive Treatment with Investigational Medication for Severe von Willebrand Disease in Children

K
Kerry Hege, MD
17 years or below
All genders
Phase 3
Interventional
This study investigates the use of prophylaxis with an investigational medication in children diagnosed with severe von Willebrand disease. Von Willebrand disease is a bleeding disorder caused by low levels or dysfunction of von Willebrand factor, a protein that helps blood clot. This study aims to evaluate the effectiveness of …
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Analysis of Circulating Pulmonary Endothelial Cells

B
Benjamin Gaston
18 years - 60 years
Accepts healthy volunteer
All genders
What is the purpose of this study?Endothelial cells line blood vessels to maintain vascular integrity and permeability. When these cells become damaged, they are shed from the lining of the blood vessels into the bloodstream and become known as circulating endothelial cells (CECs).  The purpose of this research is to …
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Workforce and System Change to Treat Adolescent Opioid Use Disorder within Integrated Pediatric Primary Care

L
Leslie Hulvershorn, MD, MSc
12 years - 100 years
All genders
Interventional
What is the purpose of this study?This project seeks to address the increasing risk of overdose death, substance use disorder (SUD), and opioid use disorder (OUD) in adolescents. The investigators believe that pediatric primary care providers (PCP) could play an important role in helping youth with SUD because most adolescents …
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Study on the Use of Investigational Medication with Targeted Therapy for Cancer that has Spread from the Pancreas

A
Anita Turk, MD
18 years or above
All genders
Phase 2
Interventional
This study investigates the use of an investigational medication along with a targeted therapy called olaparib for patients with metastatic pancreatic cancer. Metastatic pancreatic cancer is when the cancer has spread from the pancreas to other parts of the body. The study focuses on patients with specific genetic mutations called …
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