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Found 567 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

R
Raj Vuppalanchi, MD
18 years - 75 years
All genders
Interventional
To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnosticCT1 at discriminating those with NAS≥4 & F≥2 from those without.
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A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects With Non-Segmental Vitiligo Who Are Eligible for Systemic Therapy

D
David Rosmarin
12 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?Vitiligo is a common chronic autoimmune disease that causes the body's immune system to attack its own pigment producing skin cells. This study is to evaluate how safe and effective upadacitinib is in participants with non-segmental vitiligo (NSV). Adverse effects and change in disease …
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A Randomized, Double-blind, Placebo-controlled, Phase 2 Study to Evaluate the Efficacy and Safety of Anumigilimab in Patients with Hidradenitis Suppurativa Who Have Had an Inadequate Response to Anti-TNF Therapy

D
David Rosmarin
18 years - 100 years
All genders
Phase 2
Interventional
Hidradenitis suppurativa (HS) is a painful skin condition with recurring lumps, abscesses, and tunnels that drain unpleasant fluids, significantly affecting quality of life.What is the purpose of this study?The primary objective of the study is to evaluate the efficacy of anumigilimab administered in Treatment Period A to subjects with moderate …
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A Phase 3, Randomized, Double-Blind, 52-Week, Placebo-Controlled,Efficacy and Safety Study of Povorcitinib in Participants With Nonsegmental Vitiligo (Selective Treatment of Oral Povorcitinib in Vitili)

D
David Rosmarin
18 years - 75 years
All genders
Phase 3
Interventional
What is the purpose of this study?The purpose of this Study is to compare the safety and effects of povorcitinib or placebo on people with nonsegmental vitiligo.
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An open-label, phase II proof-of-concept study to evaluate the clinical efficacy and safety of tapinarof for adult patients with palmoplantar keratoderma

D
David Rosmarin
18 years - 75 years
All genders
Phase 2
Interventional
What is the purpose of this study?This study is being done to find out how safe and how well the drug Tapinarof (VTAMA) works for stopping or treating palmoplantar keratoderma, which is a condition characterized by thickened skin on your palms and soles.  Tapinarof, used as a topical 1% cream, …
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A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA) (Rezolve AA)

D
David Rosmarin
18 years - 70 years
All genders
Phase 1/2
Interventional
Why is this study being done?This study is being done to evaluate the efficacy (how well the drug works), and safety, of rezpegaldesleukin (REZPEG) at different dose levels, as compared to placebo, in adults with severe to very severe Alopecia Areata (AA), and to choose the best dose of REZPEG. …
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Using Circulating Tumor DNA to Personalize Duration of Consolidation Durvalumab

N
Nasser Hanna, MD
18 years - 100 years
All genders
Phase 2
Interventional
What is the purpose of this study?This research aims to incorporate ctDNA analysis into clinical practice to individualize therapy in patients with stage III NSCLC by moving to a treatment-by-marker based approach (as opposed to treatment based on clinical or radiographic evidence of disease).THIS STUDY IS ENROLLING BY INVITATION ONLY …
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GammaTile and Stupp in Newly Diagnosed GBM (GESTALT)

M
Mitesh Shah, MD
18 years - 100 years
All genders
Phase 4
Interventional
What is the purpose of this study?This study seeks to explore if GT, given its unique radiobiological and physical characteristics, may permit safe dose escalation and intensification and thereby provide a benefit to newly diagnosed GBM patients in terms of OS and LC when incorporated into the framework of the …
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Phase II Trial of Carboplatin +/- Tocilizumab for Metastatic Triple Negative and ER-low Breast Cancers

K
Kathy Miller, MD
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This is a randomized Phase II study of carboplatin monotherapy vs. carboplatin combined with tocilizumab in in Black and non-Black patients with metastatic triple negative or ER low breast cancer. THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, patients …
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Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

L
Lisa Landrum, MD, PhD, MS
18 years or above
Female
Phase 2/3
Interventional
What is the purpose of this study?This phase II/III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. Trastuzumab and pertuzumab are monoclonal …
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