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Found 686 results for in-health

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase III Adjuvant Trial Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression plus Endocrine Therapy in Premenopausal Patients with pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score ≤ 25 (OFSET)

T
Tarah Ballinger, MD
18 years - 60 years
Female
Phase 3
This study will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among premenopausal, early- stage breast cancer (EBC) patients with estrogen receptor (ER)-positive, HER2-negative tumors and 21-gene recurrence score (RS) …

A RANDOMIZED PHASE II TRIAL OF NIVOLUMAB AND IPILIMUMAB COMPARED TO NIVOLUMAB MONOTHERAPY IN PATIENTS WITH DEFICIENT MISMATCH REPAIR SYSTEM RECURRENT ENDOMETRIAL CARCINOMA

L
Lisa Landrum, MD, PhD, MS
18 years - 100 years
Female
Phase 2
This study tests whether the combination of nivolumab and ipilimumab is better than nivolumab alone to shrink tumors in patients with deficient mismatch repair system (dMMR) endometrial carcinoma that has come back after a period of time during which the cancer could not be detected (recurrent). Deoxyribonucleic acid (DNA) mismatch …

Study on Investigational Medication for Depressive Episodes in Youth with Bipolar Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Interventional
This study investigates the use of an investigational medication for treating depressive episodes in young people aged 10 to 17 years with Bipolar I Disorder. The study aims to see if the investigational medication is safe and works well in young people.Bipolar I Disorder is a mental health condition that …
 The Adjustment, Behavior, Language and Executive Functioning Project

The Adjustment, Behavior, Language and Executive Functioning Project (ABLE)

I
Irina Castellanos
3 years - 6 years
Accepts healthy volunteer
All genders
We are actively recruiting preschool children (both Cochlear Implant users and Normal Hearing) to participate in a new, NIH funded, longitudinal research study on psychosocial outcomes, titled The Adjustment, Behavior, Language and Executive Functioning (ABLE) Project. In the ABLE project, we investigate how preschool children’s ability to identify, plan, execute, …

A Prospective, Non-interventional (NIS), Long-term, Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

J
John Fuqua, MD
All genders
Observational
What is the purpose of this study?This is a non-interventional, observational research study of a marketed drug, Skytrofa. The purpose of this study is to evaluate the long-term effectiveness and safety of Skytrofa treatment in a large group of subjects. Skytrofa is approved in the U.S. for sale and use …
 Women Needed for Health Behaviors and Experiences Survey

Women Needed for Health Behaviors and Experiences Survey

B
Brian Dixon
18 years - 45 years
Accepts healthy volunteer
Female
Why is this study being done?Researchers at the IU School of Public Health want to better understand the health of Black and African women. The goal of this study is to explore the health behaviors, experiences, and conditions of these women which will help guide interventions to reduce the disparities …

A US Multi-center, Prospective, Non-interventional, Long Term, Effectiveness and Safety Study of Patients Treated With SKYTROFA (Lonapegsomatropin)

J
John Fuqua, MD
1 years - 17 years
All genders
Observational
Why is this study being done?This is a non-interventional, observational research study of a marketed drug, Skytrofa. These studies are carried out to identify and/or measure effects of medicines or treatment under real-life conditions.  Skytrofa is approved in the U.S. for sale and use in children with growth hormone deficiency …

MODERN: An Integrated Phase 2/3 and Phase 3 Trial of MRD-Based Optimization of ADjuvant ThErapy in URothelial CaNcer

T
Tareq Salous
18 years - 100 years
All genders
Phase 2/3
What is this study about?This phase II/III trial examines whether patients who have undergone surgical removal of bladder, but require an additional treatment called immunotherapy to help prevent their bladder cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or …
 Immune Mechanisms of Hypertension and Cardiovascular Disease

Immune Mechanisms of Hypertension and Cardiovascular Disease

M
Meena Madhur
18 years - 85 years
Accepts healthy volunteer
All genders
Why is this study being done?The Division of Clinical Pharmacology at Indiana University is looking for volunteers with and without high blood pressure to participate in a research study to better understand how the immune system regulates blood pressure and cardiovascular disease.  This study will look at the differences in …

Preclinical Validation of Adjuvant Fingolimod to Increase Efficacy of Proteasome Inhibitors for Treatment of Multiple Myeloma

A
Attaya Suvannasankha, MD
18 years - 95 years
All genders
The goal of this study is to test, in the lab, whether a new treatment may improve cancer killing and bone health in patients with multiple myeloma. Newly diagnosed patients with Multiple Myeloma will meet with PI and/or study staff (face-to-face) and given information about the study. Interested in participating? For …
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