A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the use of prophylaxis with an investigational medication in children diagnosed with severe von Willebrand disease. Von Willebrand disease is a bleeding disorder caused by low levels or dysfunction of von Willebrand factor, a protein that helps blood clot. This study aims to evaluate the effectiveness of …
What is the purpose of this study?Endothelial cells line blood vessels to maintain vascular integrity and permeability. When these cells become damaged, they are shed from the lining of the blood vessels into the bloodstream and become known as circulating endothelial cells (CECs). The purpose of this research is to …
What is the purpose of this study?This project seeks to address the increasing risk of overdose death, substance use disorder (SUD), and opioid use disorder (OUD) in adolescents. The investigators believe that pediatric primary care providers (PCP) could play an important role in helping youth with SUD because most adolescents …
This study investigates the use of an investigational medication along with a targeted therapy called olaparib for patients with metastatic pancreatic cancer. Metastatic pancreatic cancer is when the cancer has spread from the pancreas to other parts of the body. The study focuses on patients with specific genetic mutations called …
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
This study investigates treatments for patients with residual triple negative breast cancer, a type of breast cancer that does not have estrogen, progesterone, or HER2 receptors. The study uses circulating tumor DNA (ctDNA) to assign participants to different treatment arms based on their genomic markers. Participants with ctDNA positivity and …
This study investigates treatments for people with HER2-positive breast cancer. HER2-positive means that the cancer cells have more HER2 protein than normal, which can cause cancer cells to grow. The study looks at using a combination of investigational medication injections and hormone therapy after surgery. The investigational medications are trastuzumab …
What is the purpose of this study?This is a first-in-human, Phase I, open-label, multicenter study designed to evaluate they, tolerability and preliminary efficacy of WTX-124, a conditionally-activated IL-2drug, when administered as monotherapy and in combination with pembrolizumab, for thewith advanced solid tumors. THIS STUDY IS ENROLLING BY INVITATION ONLY - …
DO YOU WANT TO HELP FELLOW SURVIVORS OF COLON AND RECTAL CANCER? Join the Survivorship Plan HEalth REcord (SPHERE) study to help us deliver survivorship care tools and resources designed for people like you! We are looking for volunteers, 18 years of age or older, who have recently undergone surgery …
What is the purpose of this study?This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits ofgavivint in treating patients with solid tumors that has come back (recurrent) or does notd to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may help …
