A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
Researchers at the Indiana University School of Medicine are looking for healthy teens and adults to take part in a study to learn more about the scientific basis of sickle cell disease and to assess the effectiveness of a new treatment approach in managing the chronic and acute pain in …
This study investigates how the immune system works to prevent infections and diseases. The immune system is important for stopping infections and tumors, but problems with it can cause diseases like asthma, autoimmune diseases, and infections. The study aims to understand these inflammatory diseases better.In this study, researchers will collect …
This study investigates the genetic factors related to pediatric cardiomyopathy, a condition that affects the heart muscle's ability to function properly. Cardiomyopathy makes it difficult for the heart to pump blood effectively throughout the body. The purpose of this study is to understand how changes in genes might lead to …
Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease characterized by destruction of the interlobular bile ducts, which, if untreated, leads to fibrosis, biliary cirrhosis, and liver failure. Because liver transplantation remains the only curative option for PBC, the goals of treatment are to slow the …
What is this study about?Patients with nonalcoholic fatty liver disease have varied etiologies, associated risk factors and disease severity. One purpose of this study is to determine the possible etiological factors, risk factors, and disease severity of all patients referred to Digestive and Liver Diseases Clinics for presumed NAFLD. Another …
Primary Sclerosing Cholangitis (PSC) is a chronic liver disease that lacks treatment options short of liver transplantation. This is secondary to rarity of the disease and poor understanding of the disease pathogenesis. We are participating in a multi-center study collecting PSC patients clinical and biological information along with genetic analysis …
This is an observational study of patients with PSC to address knowledge gaps in the clinical presentation, natural history, epidemiology, progression, and outcomes.
The aim of this study is to validate the TEG 6S technology in pediatric cardiac patients by comparing its viscoelastic values with those of the standard TEG 5000.
This study will evaluate the effects of the use of a program to reduce prescribing of a group of commonly prescribed medications called anticholingerics that may adversely effect cognitive functioning in older adults.