A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?The OnPrime study is a multi-center, randomized open-label phase 3 study evaluating the safety and efficacy of Olvi-Vec followed by platinum-doublet chemotherapy and bevacizumab compared to the Active Comparator Arm with Physician's Choice of chemotherapy and bevacizumab in women diagnosed with platinum-resistant/refractory ovarian cancer …
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …
This study investigates how the immune system works to prevent infections and diseases. The immune system is important for stopping infections and tumors, but problems with it can cause diseases like asthma, autoimmune diseases, and infections. The study aims to understand these inflammatory diseases better.In this study, researchers will collect …
This study investigates how the brain makes decisions related to drinking alcohol and aims to understand addiction and the risk of developing alcoholism. The study will involve different groups of participants over several years to explore these aspects.Participants will undergo three main procedures: a phone screening, an in-person interview lasting …
This study investigates the genetic factors related to pediatric cardiomyopathy, a condition that affects the heart muscle's ability to function properly. Cardiomyopathy makes it difficult for the heart to pump blood effectively throughout the body. The purpose of this study is to understand how changes in genes might lead to …
We are looking for people of all ages, regardless of health condition, to take part in a study that is looking for new treatments for bone and muscle disorders.Bone and muscle disorders are the leading cause of disabilty in the United States. Researchers want to find out more about how …
Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease characterized by destruction of the interlobular bile ducts, which, if untreated, leads to fibrosis, biliary cirrhosis, and liver failure. Because liver transplantation remains the only curative option for PBC, the goals of treatment are to slow the …
What is this study about?Patients with nonalcoholic fatty liver disease have varied etiologies, associated risk factors and disease severity. One purpose of this study is to determine the possible etiological factors, risk factors, and disease severity of all patients referred to Digestive and Liver Diseases Clinics for presumed NAFLD. Another …
The purpose of this study is to understand how to provide better care to and improve outcomes in mothers and infants who are exposed to opioids during pregnancy in Marion County, Indiana. Care Plus will examine the various factors that may contribute to improved NAS outcomes and impact on the …
Primary Sclerosing Cholangitis (PSC) is a chronic liver disease that lacks treatment options short of liver transplantation. This is secondary to rarity of the disease and poor understanding of the disease pathogenesis. We are participating in a multi-center study collecting PSC patients clinical and biological information along with genetic analysis …