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Found 682 results for in-health

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Comparing Stigma in Lung Cancer to Other Tobacco-Related Cancers: A Study from End Lung Cancer Now

B
Bharathi Muthusamy
18 years - 100 years
All genders
This is a descriptive, cross-sectional study, which will involve a one-time survey for patients with lung cancer (any histology), pancreatic adenocarcinoma, renal cell carcinoma, and urothelial carcinoma.  Patients in this study will be recruited in a prospective basis during their in-person visit to the outpatient Multi-D Subspecialty Oncology Clinic visits at …

Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder

L
Leslie Hulvershorn, MD, MSc
10 years - 17 years
All genders
Phase 3
Interventional
This study investigates the safety and tolerability of an investigational medication in young people with schizophrenia or bipolar disorder.  Schizophrenia is a mental disorder that affects how a person thinks, feels, and behaves. Bipolar disorder is a condition that causes extreme mood swings, including emotional highs (mania or hypomania) and lows (depression)

GRONINGEN INTERNATIONAL STUDY ON SENTINEL NODES IN VULVAR CANCER III, A PROSPECTIVE PHASE II TREATMENT TRIAL

S
Sharon E. Robertson
18 years - 100 years
Female
Phase 2
The primary objective of this study is to investigate the safety of replacing inguinofemoral lymphadenectomy by chemoradiation in early stage vulvar cancer patients with a macrometastasis (>2mm) and/or extracapsular extension in the SN. The secondary objective is to evaluate the short and long-term morbidity associated with the SN procedure and …

Inhibition of Small Conductance Calcium-Activated Potassium Current: A New Therapeutic Approach for Atrial Fibrillation

J
James Tisdale
18 years - 100 years
All genders
Interventional
What is the purpose of this study?Atrial fibrillation/ atrial flutter are common irregular heart beats or arrhythmias that causes quivering of the heart and sometimes a very fast heart rate and can lead to blood clots and strokes.  Many of the current drugs on the market used to treat atrial …
 Your voice matters... Black Women Needed  to Participate in a conversation (Reproductive Health Needs of Black Women in the US)

Your voice matters... Black Women Needed to Participate in a conversation (Reproductive Health Needs of Black Women in the US)

Fatimah Lawal
R
Randolph Hubach
18 years - 45 years
Accepts healthy volunteer
Female
Do you identify as a Black or African-American Woman? We need your help by participating in a reproductive healthcare discussion! Why is this study being done?Researchers at Purdue University are exploring Black/African-American women's reproductive health needs and preferences in relation to reproductive healthcare service delivery.  We are looking for Black/African-American women …

Using Circulating Tumor DNA to Personalize Duration of Consolidation Durvalumab

N
Nasser Hanna, MD
18 years - 100 years
All genders
Phase 2
Interventional
This research aims to incorporate ctDNA analysis into clinical practice to individualize therapy in patients with stage III NSCLC by moving to a treatment-by-marker based approach (as opposed to treatment based on clinical or radiographic evidence of disease). Interested in participating? For more information about this research study or other cancer-related …

A Randomized, Double-Blind, Placebo-Controlled Phase 3b Study to Evaluate the Short- and Long-Term Efficacy and Safety of Dual Targeted Therapy With Intravenous Vedolizumab and Oral Upadacitinib Compared With Intravenous Vedolizumab Monotherapy for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

M
Monika Fischer, MD
18 years - 65 years
All genders
Phase 3
Interventional
What is the purpose of this study?The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to vedolizumab only (also called monotherapy) in adults with moderately or severely active …

Phase II Trial of Carboplatin +/- Tocilizumab for Metastatic Triple Negative and ER-low Breast Cancers

K
Kathy Miller, MD
All genders
Phase 2
Interventional
This is a randomized Phase II study of carboplatin monotherapy vs. carboplatin combined with tocilizumab in in Black and non-Black patients with metastatic triple negative or ER low breast cancer. Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, …

Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

L
Lisa Landrum, MD, PhD, MS
Female
Phase 2/3
Interventional
This phase II/III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy …

Examining Genetic Ancestry, Allostatic Load and Treatment Completion among Patients with Breast Cancer

T
Tarah Ballinger, MD
18 years - 100 years
Female
The main purpose of this study is to learn more about how genetic ancestry affects treatment completion for patients who are diagnosed with breast cancer.  Interested in participating? For more information about this research study or other cancer-related clinical trials at IU Simon Comprehensive Cancer Center, please contact:IU Clinical Trials Office Email: …
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