A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
What is the purpose of this study?This phase II trial studies how well combination chemotherapy works in treating patients withwly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FHWT) that have come back (relapsed). Drugs used in chemotherapy regimens suchH-3 (vincristine, doxorubicin, cyclophosphamide, carboplatin, etoposide, …
This study investigates the use of circulating tumor DNA (ctDNA) to personalize treatment for patients with stage III non-small cell lung cancer (NSCLC). The purpose is to use ctDNA analysis to guide therapy decisions, instead of relying solely on clinical or radiographic evidence of disease. This approach aims to tailor …
This study investigates the effects of an investigational medication alone compared to the same medication combined with tocilizumab in patients with advanced breast cancer. Advanced breast cancer includes conditions such as metastatic triple negative or ER-low breast cancer. This study involves Black and non-Black patients and aims to understand how …
This study investigates the use of abatacept in patients who have myocarditis, a heart condition, after being treated with immune checkpoint inhibitors (ICI). The purpose is to see if abatacept can lower the risk of major adverse cardiac events (MACE), which include serious heart problems like heart attacks or heart …
The purpose of this study is to examine how the immune system in humans works to prevent infections and disease. This research is focused on understanding inflammatory disease that affects millions of Americans in diseases including asthma, autoimmune disease, and infection with pathogens.
We would like to collect approximately 12 ml of blood from 200 subjects diagnosed with PBC. The blood will be separated into plasma and serum and then placed in aliquots and frozen. The samples will be used in the future for PBC research.
The purpose of this study is to understand how to provide better care to and improve outcomes in mothers and infants who are exposed to opioids during pregnancy in Marion County, Indiana.
This study will evaluate the effects of the use of a program to reduce prescribing of a group of commonly prescribed medications called anticholingerics that may adversely effect cognitive functioning in older adults.
The purpose of this study is use skin nerve activity to compare the response of the nervous system to stress within the nerves of the skin that may not be noticed in patients with transthyretin amyloidosis versus volunteers without amyloidosis.
This study is designed to be a prospective, multi-center educational intervention study to evaluate the impact of a simulator-based educational curriculum on the institutional utilization of laparoscopic common bile duct exploration (LCBDE) for the management of patients with choledocholithiasis.
