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Found 571 in-health trials

A listing of in-health medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Phase 1/2 Trial of CBL0137 in Patients with Relapsed or Refractory Solid Tumors including CNS Tumors and Lymphoma

B
Brian Weiss
1 years - 21 years
All genders
Interventional
What is the purpose of this study?This phase I/II trial evaluates the best dose, side effects and possible benefit of CBL0137 in treating patients with solid tumors, including central nervous system (CNS) tumors or lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Drugs, such as …
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Older Adults Needed for IU Bloomington Beef Intake and Muscle Fatigue Study!

Older Adults Needed for IU Bloomington Beef Intake and Muscle Fatigue Study!

C
Cydne Perry
60 years - 85 years
Accepts healthy volunteer
All genders
Are you 60-85 years of age, in overall good health, and live in the Bloomington, IN area?    Researchers at the IU School of Public Health are looking for older adults to take part in a study looking at how a beef-based diet vs. a vegetarian diet affects muscle fatigue.   All study foods …
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HAVE YOU RECENTLY TESTED POSITIVE FOR COVID? Help Us Test a New Treatment for Covid!

HAVE YOU RECENTLY TESTED POSITIVE FOR COVID? Help Us Test a New Treatment for Covid!

J
James Chmiel
M
Mike Davis
18 years - 60 years
Accepts healthy volunteer
All genders
Researchers at Indiana University School of Medicine are researching a nasal treatment for COVID-19. We are looking for people with a recent onset of mild COVID-19 symptoms and a positive COVID-19 test in the last few days to come for a 2 hour visit at Riley Hospital for Children to help …
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VOLUNTEERS AGES 21-26 NEEDED FOR ALCOHOL AND BRAIN IMAGING STUDY!

VOLUNTEERS AGES 21-26 NEEDED FOR ALCOHOL AND BRAIN IMAGING STUDY!

D
David Kareken, PhD
21 years - 27 years
Accepts healthy volunteer
All genders
Do you drink alcohol? If yes, we want to learn about your brain activity! Researchers at the IU School of Medicine are looking for volunteers aged 21-27 to participate in an alcohol and brain imaging study.Interested potential participants must complete one 3 hour in-person screening. Following the in-person screening, qualified participants in …
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Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations

A
Anita Turk, MD
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This phase II trial studies whether adding pembrolizumab to olaparib (standard of care) works better than olaparib alone in treating patients with pancreatic cancer with germline BRCA1 or BRCA2 mutations that has spread to other places in the body (metastatic). BRCA1 and BRCA2 are …
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Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7)

L
Lisa Landrum, MD, PhD, MS
18 years or above
Female
Phase 3
Interventional
What is the purpose of this study?This is a Phase 3, multicenter, open-label, randomized study of nemvaleukin in combination with pembrolizumab versus protocol-specific Investigator's choice chemotherapy in patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer.THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, …
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A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With The Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

B
Bryan Schneider, MD
18 years - 100 years
All genders
Phase 3
Interventional
What is the purpose of this study?This Phase III, randomized, open-label, multicenter study will evaluate the efficacy andy of giredestrant plus everolimus compared with the physician's choice of endocrineherapy plus everolimus in participants with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer …
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Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer (PERSEVERE)

B
Bryan Schneider, MD
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease afterve therapy will be assigned to 1 of 3 Arms based on plasma ctDNA positivity and genomic marker(s).THIS STUDY IS ENROLLING BY INVITATION ONLY - Consistent with most oncology trials, …
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PSMA-PET to Guide Prostatectomy

C
Clinton Bahler, MD
40 years - 80 years
Male
Phase 2/3
Interventional
What is the purpose of this study?This study will randomize subjects to either standard of care MRI prior to radical prostatectomy or standard of care MRI and the PSMA (prostate specific membrane antigen) PET scan prior to radical prostatectomy to see if this scan will be helpful in detecting prostate …
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A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

T
Tarah Ballinger, MD
18 years or above
All genders
Phase 2
Interventional
What is the purpose of this study?This research study is studying a combination of HER2-directed therapies (trastuzumab anduzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer. The study drugs involved in this study are: A combination of trastuzumab and pertuzumab given as an injection …
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